Testicular germ cell tumor
MONDO:0010108A germ cell tumor arising from the testis. Representative examples include teratoma, seminoma, embryonal carcinoma, and yolk sac tumor.
Also known as: TGCT, germ cell neoplasm of testis, germ cell neoplasm of the testis, germ cell tumor of testis, germ cell tumor of the testis, germ cell tumors, somatic, germ cell tumour of testis, germ cell tumour of the testis
1480 clinical trials for this condition and its sub-types, 13 tagged with Testicular germ cell tumor itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Testicular germ cell tumor
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Malignant testicular germ cell tumor 14 trials · 36 incl. sub-types
6 sub-types
- Testis refractory cancer 13 trials
- Testicular seminoma 8 trials Sub-types →
- Testicular non-seminomatous germ cell cancer 3 trials · 4 incl. sub-types Sub-types →
- Mixed testicular germ cell cancer 2 trials Sub-types →
- Malignant teratoma of testis 0 trials
- Testis polyembryoma 0 trials
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Testicular non-seminomatous germ cell tumor 7 trials · 9 incl. sub-types
2 sub-types
- Testicular non-seminomatous germ cell cancer 3 trials · 4 incl. sub-types Sub-types →
- Testicular trophoblastic tumor 0 trials · 1 incl. sub-types Sub-types →
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Testicular pure germ cell tumor 0 trials · 9 incl. sub-types
4 sub-types
- Testicular seminoma 8 trials Sub-types →
- Testicular embryonal carcinoma 1 trial · 2 incl. sub-types Sub-types →
- Testicular trophoblastic tumor 0 trials · 1 incl. sub-types Sub-types →
- Testicular yolk sac tumor 1 trial Sub-types →
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Childhood testicular germ cell tumor 0 trials
3 sub-types
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Testicular germ cell tumor 1 0 trials
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Testicular teratoma 0 trials
Most studied deeper sub-types
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Can a glowing dye and a gamma probe spare testicular cancer patients from chemo?
Disease control Recruiting nowThis trial tests whether combining two imaging techniques—a radioactive tracer and a fluorescent dye—can better identify sentinel lymph nodes in men with testicular seminoma. The goal is to see if this approach can accurately show whether cancer has spread, potentially allowing s…
Sponsor: N.N. Petrov National Medical Research Center of Oncology • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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New antibody drug enters first human tests for tough cancers
Disease control Recruiting nowThis early-stage trial is testing a new drug called XmAb541 in people with advanced ovarian, endometrial, or germ cell tumors that have not responded to standard treatments. The main goal is to see if the drug is safe and to find the best dose. About 282 participants will receive…
Phase 1 • Sponsor: Xencor, Inc. • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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New hope for rare cancers: drug combo shows promise in early trial
Disease control Recruiting nowThis phase 2 trial is testing a combination of two drugs, enfortumab vedotin and pembrolizumab, in people with rare cancers of the bladder, urinary tract, or testicles. The study aims to see if these drugs can shrink tumors or slow disease progression. About 68 adults will receiv…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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Blood test may spot active testicular cancer, study seeks proof
Diagnosis Recruiting nowThis study is testing whether a blood test that measures a substance called miRNA-371 can accurately detect active testicular cancer in people who have already had their primary tumor removed. Researchers will compare the blood test results with surgical findings to see how well …
Sponsor: University of Southern California • Aim: Diagnosis
Last updated Aug 22, 2026 00:00 UTC
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Bile acids may reveal testicular cancer secrets
Knowledge-focused Recruiting nowThis study looks at bile acid levels in the blood and tumor tissue of 20 men with testicular germ cell cancer. Researchers want to see if these levels can serve as markers to predict how the disease will progress and how well it responds to treatment. The goal is to improve monit…
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Blood marker may outshine scans for testicular cancer detection
Knowledge-focused Recruiting nowThis observational study is testing whether a blood marker called miRNA371 can detect active germ cell tumors more accurately than standard imaging. Researchers will collect blood samples and perform scans on 100 adults newly diagnosed with germ cell tumors. The goal is to see if…
Sponsor: Fondazione del Piemonte per l'Oncologia • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC