Tauopathy
MONDO:0005574Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (tau proteins) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with alzheimer disease; dementia; parkinsonian disorders; progressive supranuclear palsy (supranuclear palsy, progressive); and corticobasal degeneration.
1193 clinical trials for this condition and its sub-types, 24 tagged with Tauopathy itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Tauopathy
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Alzheimer disease 1,187 trials
5 sub-types
- Familial Alzheimer disease 13 trials · 55 incl. sub-types Sub-types →
- Alzheimer disease 16 1 trial
- Alzheimer disease 17 1 trial
- Alzheimer disease 18 1 trial
- Alzheimer disease 19 1 trial
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Argyrophilic grain disease 0 trials
Most studied deeper sub-types
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New drug targets brain inflammation to slow Alzheimer's
Disease control CompletedThis study tested an experimental drug called XPro1595 in 208 people with early Alzheimer's disease who also had signs of brain inflammation. The goal was to see if the drug could improve memory, thinking, and daily function compared to a placebo over 24 weeks. Researchers also c…
Phase 2 • Sponsor: Inmune Bio, Inc. • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Could this pill slow Alzheimer's? new trial results are in
Disease control CompletedThis completed Phase 2 trial tested an oral drug called LY3372689 in 327 people with early symptomatic Alzheimer's disease. The goal was to see if the drug could safely slow down declines in thinking and daily living skills compared to a placebo. The study focused on participants…
Phase 2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 13:08 UTC
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New PET tracers aim to spot tau tangles in rare brain disease
Diagnosis CompletedThis early-phase study tests two new imaging drugs, [18F]ABBV-964i and [18F]ABBV-965i, designed to light up tau protein buildup in the brain during a PET scan. Tau buildup is linked to Progressive Supranuclear Palsy (PSP), a rare movement and thinking disorder. The trial includes…
Early phase 1 • Sponsor: Invicro • Aim: Diagnosis
Last updated Jul 12, 2026 00:00 UTC
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Blood test may spot Alzheimer's without painful spinal tap
Diagnosis CompletedThis study looked at whether a blood test can accurately diagnose Alzheimer's disease, compared to the current standard of testing spinal fluid. Researchers measured specific proteins in the blood of 342 adults visiting memory clinics. The goal was to see if these blood markers c…
Sponsor: University Hospital, Montpellier • Aim: Diagnosis
Last updated Jun 27, 2026 08:07 UTC