T lymphoblastic leukemia/lymphoma
MONDO:0003537A neoplasm of lymphoblasts committed to the T-cell lineage, typically composed of small to medium-sized blast cells. When the neoplasm involves predominantly the bone marrow and the peripheral blood, it is called T acute lymphoblastic leukemia. When it involves nodal or extranodal sites it is called T lymphoblastic lymphoma. (WHO, 2001)
Also known as: precursor T lymphoblastic leukemia/lymphoma, precursor T lymphoblastic lymphoma/leukemia, precursor T-lymphoblastic lymphoma/leukemia
1945 clinical trials for this condition and its sub-types, 18 tagged with T lymphoblastic leukemia/lymphoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of T lymphoblastic leukemia/lymphoma
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T-lymphoblastic lymphoma 32 trials
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T-cell prolymphocytic leukemia 17 trials
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Childhood precursor T-lymphoblastic lymphoma/leukemia 0 trials · 13 incl. sub-types
2 sub-types
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Aggressive NK-cell leukemia 11 trials
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New maintenance therapy shows promise in preventing T-Cell cancer relapse after transplant
Disease control CompletedThis study tested whether a low dose of the drug chidamide, given after a donor stem cell transplant, can help prevent T-cell acute lymphoblastic leukemia or T-cell lymphoma from coming back. Forty-four patients aged 14 to 70 who were at high risk of relapse took part. The main g…
Phase 2 • Sponsor: Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Experimental combo aims to boost stem cell transplant for rare blood cancers
Disease control CompletedThis early-phase trial tested whether adding the drug romidepsin before and after a stem cell transplant could help control T-cell cancers like lymphoma and leukemia. Twenty-three patients received romidepsin along with standard chemotherapy, followed by a donor stem cell transpl…
Phase 1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 26, 2026 18:59 UTC
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Can a fitness tracker and coaching get teens with leukemia moving?
Symptom relief CompletedThis study tested whether a mobile health program—including a Fitbit with movement reminders, coaching sessions, and a WhatsApp peer support group—could help 20 adolescents and young adults with acute lymphoblastic leukemia (ALL) reduce the time they spend sitting or lying down d…
Sponsor: Children's Hospital Los Angeles • Aim: Symptom relief
Last updated Jul 09, 2026 00:00 UTC