T-cell large granular lymphocyte leukemia
MONDO:0019469T-cell large granular lymphocyte leukemia (T-cell LGL leukemia) is a lymphoproliferative malignancy that arises from the mature T-cell (CD3+) lineage.
Also known as: LGLL, T gamma lymphoproliferative disorder, T-LGL, T-LGL leukaemia, T-LGL leukemia, T-cell LGL leukaemia, T-cell LGL leukemia, T-cell large gran. lymph. leuk.
1962 clinical trials for this condition and its sub-types, 18 tagged with T-cell large granular lymphocyte leukemia itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →-
New drug ABC008 tested for rare blood cancer
Disease control CompletedThis study tested a new drug called ABC008 in 21 adults with T-cell large granular lymphocytic leukemia (T-LGLL), a rare blood cancer. The drug was given as a shot under the skin. The main goal was to check for side effects and see how the drug affects blood counts and other lab …
Phase 1/2 • Sponsor: Abcuro, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
-
New Two-Step transplant shows promise for blood cancer patients
Disease control CompletedThis study tested a two-step stem cell transplant for people with blood cancers like leukemia and lymphoma. First, patients received low-dose chemotherapy and radiation to prepare their bodies. Then, they got donor stem cells followed by drugs to prevent the donor cells from atta…
Phase 2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
-
Experimental combo aims to boost stem cell transplant for rare blood cancers
Disease control CompletedThis early-phase trial tested whether adding the drug romidepsin before and after a stem cell transplant could help control T-cell cancers like lymphoma and leukemia. Twenty-three patients received romidepsin along with standard chemotherapy, followed by a donor stem cell transpl…
Phase 1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 26, 2026 18:59 UTC