Systemic-onset juvenile idiopathic arthritis
MONDO:0019434Systemic-onset juvenile idiopathic arthritis is marked by the severity of the extra-articular manifestations (fever, cutaneous eruptions) and by an equal sex ratio.
Also known as: SoJIA, Still disease, sJIA, systemic polyarthritis, systemic-onset JIA, Still's disease (formerly), systemic juvenile idiopathic arthritis, systemic onset juvenile idiopathic arthritis
59 clinical trials for this condition and its sub-types, 25 tagged with Systemic-onset juvenile idiopathic arthritis itself.
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New drug combo aims to tame rare inflammatory disease
Disease control Not yet recruitingThis study tests two experimental drugs, goflikicept and olokizumab, in 52 adults with Still's disease, a rare inflammatory condition. The goal is to see if these drugs can quickly bring the disease under control and keep it from flaring up. Participants will receive either the s…
Phase 3 • Sponsor: R-Pharm International, LLC • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New blood markers may speed up diagnosis of childhood arthritis and fevers
Diagnosis Not yet recruitingThis study looks at two substances in the blood, IL-18 and IL-18BP, to see if they can help doctors tell apart different causes of fever in children. Researchers will measure these levels in 9 children with conditions like juvenile arthritis, autoinflammatory diseases, or serious…
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Diagnosis
Last updated Jun 27, 2026 11:01 UTC
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Can doctors match the right arthritis drug to the right child?
Knowledge-focused Not yet recruitingResearchers at Sohag University are following 50 children under 18 who have systemic juvenile idiopathic arthritis, a rare inflammatory disease that affects the whole body. The study records each child's symptoms, lab results, complications, and the treatments they receive, inclu…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Sep 13, 2026 00:00 UTC
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Immune clues in the blood may foretell heart trouble
Knowledge-focused Not yet recruitingThis study is building a biobank of blood samples and imaging data from 300 people with suspected inflammatory heart or autoimmune rheumatic diseases. Researchers aim to identify immune biomarkers that could predict major heart events like heart failure, stroke, or atrial fibrill…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Aug 12, 2026 00:00 UTC