Stage I endometrioid carcinoma
MONDO:0004961Endometrial cancer is a cancer that arises from the endometrium (the lining of the uterus or womb).It is the result of the abnormal growth of cells that have the ability to invade or spread to other parts of the body. The first sign is most often vaginal bleeding not associated with a menstrual period. Other symptoms include pain with urination or sexual intercourse, or pelvic pain. Endometrial cancer occurs most commonly after menopause. In stage I, the cancer is only growing in the body of the uterus. It may also be growing into the glands of the cervix, but is not growing into the supporting connective tissue of the cervix.
2854 clinical trials for this condition and its sub-types, 16 tagged with Stage I endometrioid carcinoma itself.
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Could a hormonal IUD replace surgery for some uterine cancers?
Disease control OngoingThis study looks at whether a hormonal intrauterine device (IUD) alone or combined with the drug everolimus can treat precancerous changes or very early-stage endometrial cancer. About 100 women with these conditions will receive the IUD, and some will also take everolimus if the…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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Immunotherapy plus radiation may keep endometrial cancer from returning
Disease control OngoingThis study tests whether adding the immunotherapy drug pembrolizumab to standard radiation therapy can better prevent cancer recurrence in people with newly diagnosed, early-stage endometrial cancer that has a specific genetic feature (mismatch repair deficiency). About 164 parti…
Phase 3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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Promising scan study for endometrial cancer pulled before it started
Knowledge-focused CancelledThis study aimed to see if a type of PET/MRI scan could predict which women with early endometrial cancer or a precancerous condition would respond to hormone therapy. It planned to enroll 8 women and follow them for 6 months. However, the study was withdrawn before any participa…
Phase 2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC