Spinocerebellar ataxia type 6
MONDO:0008457Spinocerebellar ataxia type 6 (SCA6) is the most common subtype of autosomal dominant cerebellar ataxia type III (ADCA type III) characterized by late-onset and slowly progressive gait ataxia and other cerebellar signs such as impaired muscle coordination and nystagmus.
Also known as: CACNA1A autosomal dominant cerebellar ataxia type III, SCA6, autosomal dominant cerebellar ataxia type III caused by mutation in CACNA1A, spinocerebellar ataxia type 6, spinocerebellar ataxia 6
30 clinical trials for this condition and its sub-types, 9 tagged with Spinocerebellar ataxia type 6 itself.
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Brain implant that learns could help rare movement disorder
Disease control Recruiting nowThis early study tests whether a smart brain implant can help people with spinocerebellar ataxia type 6, a condition that causes trouble with balance and coordination. Five adults will get the implant, which records brain signals and adjusts stimulation automatically. The goal is…
Sponsor: University of Florida • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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Brain implant adapts in real time to help ataxia patients move better
Disease control Recruiting nowThis early study tests whether a deep brain stimulator placed in the cerebellum can safely improve movement and balance in 5 adults with spinocerebellar ataxia type 6. The device automatically adjusts its stimulation based on the person's brain signals. The goal is to see if this…
Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Could a simple amino acid ease rare brain disorders?
Symptom relief Recruiting nowThis study tests a drug called N-acetyl-L-leucine for people aged 4 and older with CACNA1A gene disorders, which can cause coordination problems, dizziness, and migraines. About 60 participants will receive either the drug or a placebo, then switch, to see if it improves movement…
Phase 3 • Sponsor: IntraBio Inc • Aim: Symptom relief
Last updated Sep 10, 2026 00:00 UTC
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Can we predict how genetic ataxias progress?
Knowledge-focused Recruiting nowThis study follows people with several types of spinocerebellar ataxia (SCA) — rare genetic diseases that cause balance, coordination, and speech problems — to learn how these conditions change over time. Researchers will collect blood samples, perform neurological exams, and use…
Sponsor: Lauren Moore • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC