Spinal injury

This trial tests whether injecting bone cement into a recently fractured vertebra (vertebroplasty) reduces disability better than wearing a brace. Adults aged 18–70 with a traumatic spinal fracture (within 15 days) are randomly assigned to one of the two treatments. The study mea…

This study tested a new gel-like product that helps stop bleeding during spinal surgery. It was compared to an existing product in 130 patients with spinal stenosis, tumors, or injuries. The goal was to see if the new product works just as well and is safe to use.

This trial tests whether contrast-enhanced ultrasound can detect spinal cord injury during decompression surgery for chronic spinal cord compression. Researchers inject an ultrasound contrast agent before, during, and after the procedure to visualize blood flow changes in the spi…

This trial tests whether oxytocin nasal spray can prevent postoperative delirium—a state of confusion that can occur after surgery—in older adults undergoing orthopedic procedures. Participants aged 65 and older will receive the spray before the end of anesthesia and twice daily …

This study tests whether dantrolene, a non-sedating muscle relaxant, can improve pain control and reduce agitation in adults undergoing lumbar fusion surgery. Participants receive either dantrolene or a placebo pill before and after surgery. The goal is to see if dantrolene impro…

This study tested a 20-minute neck-strengthening program in 50 amateur rugby players to see if it could speed up their neck muscle reactions to head impacts. The program used isometric contractions and stroboscopic glasses to improve visual processing and reflex force. Researcher…

This study tested whether wearing earplugs and an eye mask during an MRI scan can lower anxiety. 72 adults having their first MRI were split into two groups: one used the earplugs and eye mask, the other did not. Researchers measured changes in blood pressure, heart rate, breathi…

This study compared two pain relief methods for people undergoing lower back decompression surgery. One group received a nerve block (erector spinae plane block), while the other received ketamine through an IV. Researchers measured how well patients recovered using a quality-of-…

This study tested a combination of three procedures—spinal fixation, nerve heat treatment, and anti-inflammatory injections—for people with ongoing back and leg pain after disc surgery. 63 participants were split into two groups to see if the triple approach worked better than sp…

This study gathered information from 193 adults who had surgery or orthopedic treatment for spine problems. Researchers collected clinical, functional, and social data to create a detailed database. The goal was to better understand patient outcomes and standardize how data is co…

This study tested a new lightweight device called PYTHEAS ODYSSEE that helps surgeons place screws in the spine more accurately. Fourteen adults having spine surgery used the device to guide screw placement. The goal was to see if the device reduces screw misplacement and is safe…

This study looked at three different ways to close surgical wounds after spine surgery. Researchers measured blood flow around the wound to see if one method was better. The study involved 50 adults with spinal stenosis who had back surgery at Mayo Clinic.

This study involved over 22,000 children who experienced blunt trauma (like car crashes or falls) to develop a tool that helps doctors decide which kids truly need neck immobilization and imaging. The goal is to avoid unnecessary X-rays and CT scans, which expose children to radi…

This study collected information from over 8,000 people who had spine surgery for conditions like degeneration, deformity, or trauma. Researchers gathered X-ray and health data to learn which treatments work best for different patients. The goal was to build a database to answer …

This completed study looked at 150 adults with thoraco-lumbar spine injuries to see if adding an emergency MRI to a standard CT scan changes how doctors treat them. The researchers compared treatment plans before and after the MRI, including options like rest, minimally invasive …