Sphingolipidosis
MONDO:0019255An inherited metabolic disorder that affects the lysosomal degradation of the spinhgolipids. Representative examples include Gaucher disease, Tay-Sachs disease, and Niemann-Pick disease.
166 clinical trials for this condition and its sub-types, 6 tagged with Sphingolipidosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Sphingolipidosis
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Fabry disease 64 trials
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Gaucher disease 46 trials
5 sub-types
- Gaucher disease type I 12 trials
- Gaucher disease type III 12 trials
- Gaucher disease type II 5 trials
- Gaucher disease perinatal lethal 0 trials
- Gaucher disease-ophthalmoplegia-cardiovascular calcification syndrome 0 trials
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Gangliosidosis 3 trials · 24 incl. sub-types
2 sub-types
- GM2 gangliosidosis 14 trials · 19 incl. sub-types Sub-types →
- GM1 gangliosidosis 12 trials Sub-types →
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Niemann-Pick disease 10 trials · 22 incl. sub-types
4 sub-types
- Niemann-Pick disease type C 12 trials · 13 incl. sub-types Sub-types →
- Acid sphingomyelinase deficiency 7 trials · 10 incl. sub-types Sub-types →
- Niemann-Pick disease type E 0 trials
- Chronic neurovisceral acid sphingomyelinase deficiency 0 trials
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Metachromatic leukodystrophy 20 trials
2 sub-types
- Metachromatic leukodystrophy, juvenile form 2 trials · 4 incl. sub-types Sub-types →
- Metachromatic leukodystrophy due to saposin B deficiency 0 trials
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Krabbe disease 15 trials
3 sub-types
- Infantile Krabbe disease 2 trials
- Adult Krabbe disease 0 trials
- Late-infantile/juvenile Krabbe disease 0 trials
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Mucosulfatidosis 4 trials
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ASAH1-related sphingolipidosis 0 trials · 1 incl. sub-types
2 sub-types
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PSAP-related sphingolipidosis 0 trials · 1 incl. sub-types
4 sub-types
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Sea-blue histiocyte syndrome 0 trials
Most studied deeper sub-types
Sandhoff disease
(13)
Tay-Sachs disease
(13)
Niemann-Pick disease type A
(4)
GM1 gangliosidosis type 1
(3)
GM1 gangliosidosis type 2
(3)
Tay-Sachs disease, B variant, adult form
(3)
Metachromatic leukodystrophy, late infantile form
(2)
Niemann-Pick disease, type C1
(2)
Niemann-Pick disease type B
(1)
Niemann-Pick disease, type C2
(1)
Sandhoff disease, adult form
(1)
Tay-Sachs disease, b variant, juvenile form
(1)
GM1 gangliosidosis type 3
(0)
Metachromatic leukodystrophy, adult form
(0)
Niemann-Pick disease type C, adult neurologic onset
(0)
Niemann-Pick disease type C, juvenile neurologic onset
(0)
Niemann-Pick disease type C, late infantile neurologic onset
(0)
Niemann-Pick disease type C, severe early infantile neurologic onset
(0)
Niemann-Pick disease type C, severe perinatal form
(0)
Sandhoff disease, infantile form
(0)