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Spermatogenic failure 3
MONDO:0011720Any azoospermia in which the cause of the disease is a mutation in the SLC26A8 gene.
Also known as: SLC26A8 azoospermia, azoospermia caused by mutation in SLC26A8, spermatogenic failure 3, spermatogenic failure type 3, SPGF3
12 clinical trials for this condition and its sub-types, 9 tagged with Spermatogenic failure 3 itself.
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Could a blood draw help men with no sperm become fathers?
Disease control Recruiting nowThis Stanford study tests whether injecting a man's own platelet-rich plasma (PRP) into his testicles can help produce sperm. Ten men with nonobstructive azoospermia who previously failed sperm retrieval will receive the injection. Three months later, doctors will check for sperm…
Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Mitochondrial DNA mutation may be a hidden cause of male infertility
Knowledge-focused Recruiting nowThis study investigates whether a specific mitochondrial DNA variant (MT-ND1 m.3700G>A) is associated with severe male infertility, specifically conditions where sperm production is absent or extremely low. Researchers analyzed existing medical records and biological samples from…
Sponsor: The Third Affiliated Hospital of Guangzhou Medical University • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Can your genes explain infertility? new study seeks answers
Knowledge-focused Recruiting nowThis study aims to find genes that may cause infertility in people with non-obstructive azoospermia (low or no sperm) or primary ovarian insufficiency (early menopause). Researchers will collect saliva samples from 500 adults to look for genetic differences. No new treatments are…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC