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Skull base chordoma
MONDO:0002892A slow-growing malignant bone tumor arising from the remnants of the notochord and occurring in the base of the skull. It is characterized by a lobulated growth pattern, myxoid stroma formation, and the presence of physaliphorous cells..
Also known as: chordoma of skull base, chordoma of the skull base, skull base chordoma
2851 clinical trials for this condition and its sub-types, 5 tagged with Skull base chordoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Skull base chordoma
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Clivus chordoma 0 trials
1 sub-type
- Clivus chondroid chordoma 0 trials
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Precision proton beams take aim at rare bone cancers
Disease control OngoingThis study tests a precise type of proton radiation (IMPT) for people with chordoma or chondrosarcoma in the spine, sacrum, or skull base. The goal is to control the tumor while reducing damage to healthy tissue. Some participants may also have surgery. The study includes 64 adul…
Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Proton beam therapy tested for rare skull base tumor
Disease control OngoingThis Phase II trial is studying whether proton beam therapy, with or without standard photon radiation, can effectively treat skull base chordoma, a rare tumor at the base of the skull. Nineteen participants who had surgery to remove as much tumor as possible are receiving daily …
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC