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Shigellosis
MONDO:0019345Shigellosis is a bacterial infection leading to dysentery and is caused by Shigella, which are small, ubiquitous Gram-negative bacteria belonging to the enterobacteria family. There are four species: S. dysenteriae, S. flexneri, S. boydii and S. sonnei, all of which cause bacillary dysentery and are strictly limited to human hosts.
Also known as: shigellosis, Shigella boydii infectious disease, Shigella flexneri infectious disease, Shigella sonnei infectious disease, Shigella dysentery, flexner's dysentery, japanese dysentery
19 clinical trials for this condition and its sub-types, 14 tagged with Shigellosis itself.
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New vaccine trial targets deadly diarrhea bug
Vaccine Recruiting nowThis early-stage study tests a new vaccine called IVT Shigella-04 to see if it is safe and helps the immune system fight Shigella bacteria, a major cause of severe diarrhea. About 60 healthy adults aged 18 to 49 will receive two shots of either the vaccine or a placebo. Researche…
Phase 1 • Sponsor: Inventprise Inc. • Aim: Vaccine
Last updated Jun 27, 2026 07:58 UTC
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Could a simple antibiotic stop shigella from stunting Kids' growth?
Disease control Recruiting nowThis study looks at whether giving antibiotics to children with a certain type of Shigella infection (non-dysentery watery diarrhea) helps them recover faster and grow better. About 700 children in Bangladesh and Zambia will receive either azithromycin or a placebo. Researchers w…
Phase 2 • Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC