Severe hemophilia B
MONDO:0015715Severe hemophilia B is a form of hemophilia B characterized by a large deficiency of factor IX leading to frequent spontaneous hemorrhage and abnormal bleeding as a result of minor injuries, or following surgery or tooth extraction.
Also known as: severe factor IX deficiency, severe haemophilia type B, severe hemophilia type B
22 clinical trials for this condition and its sub-types, 9 tagged with Severe hemophilia B itself.
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Monthly shot could free kids with hemophilia from frequent infusions
Disease control CompletedThis study tests fitusiran, a monthly injection, in boys aged 1 to under 12 with severe hemophilia A or B who have developed inhibitors (antibodies that block standard treatment). The goal is to find the right dose to safely lower a protein called antithrombin, which helps preven…
Phase 3 • Sponsor: Genzyme, a Sanofi Company • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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New hemophilia shot shows early promise in small safety trial
Disease control CompletedThis early-phase study tested a new drug called MG1113, given as a shot under the skin, in 15 adults with severe hemophilia A or B. The main goal was to check safety and how the drug moves through the body. Participants received multiple doses to see if the drug is well-tolerated…
Phase 1 • Sponsor: GC Biopharma Corp • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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New monitoring methods tested for haemophilia b treatment
Knowledge-focused CompletedThis completed study involved 15 people with severe haemophilia B who were already taking eftrenonacog-alfa, a clotting factor medicine. Researchers compared different lab tests to see which ones best measure factor IX activity in real-life conditions. The goal was to improve mon…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC