Severe hemophilia B
MONDO:0015715Severe hemophilia B is a form of hemophilia B characterized by a large deficiency of factor IX leading to frequent spontaneous hemorrhage and abnormal bleeding as a result of minor injuries, or following surgery or tooth extraction.
Also known as: severe factor IX deficiency, severe haemophilia type B, severe hemophilia type B
22 clinical trials for this condition and its sub-types, 9 tagged with Severe hemophilia B itself.
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New shot could cut bleeds in kids with hemophilia
Disease control Recruiting nowThis phase 3 trial is testing a drug called fitusiran in about 85 boys aged 1 to under 12 with severe hemophilia A or B, including those with inhibitors that make standard treatments less effective. The drug is given as a regular shot under the skin to help prevent bleeding episo…
Phase 3 • Sponsor: Sanofi • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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New blood test could improve bleeding control for hemophilia patients
Knowledge-focused Recruiting nowThis study aims to create a reliable lab test to monitor how well anti-TFPI antibodies work in people with severe hemophilia. Researchers will take a single blood sample from 11 patients already on anti-TFPI therapy and test it in the lab. The goal is to better predict and manage…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC