Secondary progressive multiple sclerosis

MONDO:0000450

A multiple sclerosis with a clinical course characterized by a progressive accumulation of neurological disability, independent of relapses, following an initial relapsing-remitting (RR) phase.

Also known as: SPMS, secondary-progressive MS

113 clinical trials for this condition and its sub-types, 65 tagged with Secondary progressive multiple sclerosis itself.

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Where it sits in the disease tree

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Part of

↑ Chronic progressive multiple sclerosis (113)

Including sub-types (113) Tagged with Secondary progressive multiple sclerosis (65)

Trials to join now! 24 Not yet recruiting 9 Not yet finished but already full! 18 Completed 13 Terminated 1

MS drug trial halted after failing to lower nerve damage

Disease control Stopped early

This study tested an oral drug called SAR443820 in 174 adults with multiple sclerosis (MS) to see if it could lower a marker of nerve damage in the blood. The trial was stopped early because the drug did not meet its main goal of reducing that marker. Participants were followed f…

Phase 2 • Sponsor: Sanofi • Aim: Disease control

Last updated Jun 27, 2026 07:54 UTC

Secondary progressive multiple sclerosis

Where it sits in the disease tree

MS drug trial halted after failing to lower nerve damage