Sclerosing cholangitis

MONDO:0018646

A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure.

Also known as: Primary sclerosing cholangitis, primary sclerosing cholangitis (PSC), sclerosing cholangitis, sclerosing cholangitis (disease)

60 clinical trials for this condition and its sub-types, 3 tagged with Sclerosing cholangitis itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Cholangitis (139)

Sub-types of Sclerosing cholangitis

Primary sclerosing cholangitis 54 trials
1 sub-type
- Nephropathy, progressive tubulointerstitial, with cholestatic liver disease 0 trials
Secondary sclerosing cholangitis 2 trials
IgG4-related sclerosing cholangitis 0 trials
Isolated neonatal sclerosing cholangitis 0 trials
Neonatal ichthyosis-sclerosing cholangitis syndrome 0 trials

Including sub-types (60) Tagged with Sclerosing cholangitis (3)

Trials to join now! 1 Not yet finished but already full! 1 Completed 1

New study tracks rare liver disease in kids to uncover clues

Knowledge-focused Recruiting now

This study follows 1,000 children with primary sclerosing cholangitis (PSC), a rare liver disease that damages bile ducts. Researchers will collect medical data, DNA, and symptom reports over time to understand how the disease progresses and affects daily life. The goal is to ide…

Sponsor: Arbor Research Collaborative for Health • Aim: Knowledge-focused

Last updated Jul 16, 2026 00:00 UTC

Sclerosing cholangitis

Where it sits in the disease tree

New study tracks rare liver disease in kids to uncover clues