Sciatic neuropathy
MONDO:0006960Disease or damage involving the SCIATIC NERVE, which divides into the PERONEAL NERVE and TIBIAL NERVE (see also PERONEAL NEUROPATHIES and TIBIAL NEUROPATHY). Clinical manifestations may include SCIATICA or pain localized to the hip, PARESIS or PARALYSIS of posterior thigh muscles and muscles innervated by the peroneal and tibial nerves, and sensory loss involving the lateral and posterior thigh, posterior and lateral leg, and sole of the foot. The sciatic nerve may be affected by trauma; ISCHEMIA; COLLAGEN DISEASES; and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1363)
77 clinical trials for this condition and its sub-types, 9 tagged with Sciatic neuropathy itself.
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Sub-types of Sciatic neuropathy
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Sciatica 46 trials · 68 incl. sub-types
1 sub-type
- Piriformis syndrome 25 trials
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Lesion of sciatic nerve 2 trials
2 sub-types
- Common peroneal nerve lesion 0 trials
- Plantar nerve lesion 0 trials
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Can a drug melt away painful scar tissue after back surgery?
Disease control CompletedThis study tested whether a drug that blocks TNF-alpha, a protein involved in inflammation and scar formation, can reduce sciatica pain in people who developed spinal scar tissue after back surgery. 38 adults with persistent pain after discectomy received either the drug or a pla…
Phase 3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Tiny camera surgery may beat standard back procedure for faster pain relief
Symptom relief CompletedThis completed study compared two minimally invasive surgeries for herniated discs: full endoscopic lumbar discectomy (FELD) and microdiscectomy (MD). Researchers enrolled 200 adults aged 18-85 with single-level disc herniation and sciatica. The goal was to see which technique pr…
Sponsor: University of Opole • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC