Schizophrenia 1
MONDO:0008414A schizophrenia that has material basis in an autosomal dominant mutation of SCZD1 on chromosome 5q23-q35.
Also known as: SCZD1, schizophrenia 1, schizophrenia 1 with or without an affective disorder, schizophrenia susceptibility locus, chromosome 5-related
96 clinical trials for this condition and its sub-types, 28 tagged with Schizophrenia 1 itself.
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Could a simple walk recalibrate the Brain's sense of self?
Knowledge-focused Recruiting nowThis trial explores whether physical activity, specifically walking in different visual environments, can improve the sense of self in people with schizophrenia, borderline personality disorder, or vestibular syndromes. Participants will complete walking sessions in three environ…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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Spotting psychosis early could change lives — a major study tests whether faster treatment leads to better recovery
Knowledge-focused Recruiting nowThis study investigates whether early-detection programs for psychosis can reduce the time people live with untreated symptoms and whether that leads to better long-term functioning. Researchers will follow adults newly diagnosed with schizophrenia-spectrum disorders in two Danis…
Sponsor: Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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Brain scans reveal how new schizophrenia drug cobenfy works
Knowledge-focused Recruiting nowThis study will use brain scans (PET/MRI) to see how the drug Cobenfy affects dopamine in the brains of 12 people with schizophrenia. Participants will take one of three doses of Cobenfy for 5 weeks and get a brain scan before and after treatment. The goal is to understand how th…
Phase 1/2 • Sponsor: New York State Psychiatric Institute • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
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Zapping the brain to read faces: new hope for schizophrenia?
Knowledge-focused Recruiting nowThis study tests whether a gentle electrical current applied to the scalp (tDCS) can improve how people with schizophrenia recognize emotions in faces. Researchers will use brain scans to see if the stimulation changes activity in motion-processing areas. The goal is to understan…
Sponsor: Nathan Kline Institute for Psychiatric Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Can trauma therapy help those with psychosis? new study aims to find out
Knowledge-focused Recruiting nowThis pilot study is testing whether two established trauma therapies—Prolonged Exposure and EMDR—can be safely used in young adults with psychotic disorders who also have PTSD symptoms. Twenty participants from the OPUS early-intervention program will receive one of the therapies…
Sponsor: Nikolai Albert • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC