Rhabdoid tumor of the kidney
MONDO:0002729A rhabdoid tumor that arises from the kidney. It occurs in children and it is associated with abnormalities of chromosome 22. It is characterized by the presence of cells with a large eccentric nucleus, prominent nucleolus, and abundant cytoplasm. The prognosis is poor.
Also known as: MRTK, kidney rhabdoid tumor, kidney rhabdoid tumour, malignant rhabdoid tumor of kidney, malignant rhabdoid tumor of the kidney, malignant rhabdoid tumour of kidney, malignant rhabdoid tumour of the kidney, renal rhabdoid neoplasm
2859 clinical trials for this condition and its sub-types, 7 tagged with Rhabdoid tumor of the kidney itself.
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New drug cocktail targets rare, aggressive kidney cancer
Disease control CompletedThis phase II trial is testing whether combining the targeted drug ixazomib with two chemotherapy drugs (gemcitabine and doxorubicin) can shrink tumors or stop them from growing in patients with a rare and aggressive kidney cancer called renal medullary carcinoma. The study enrol…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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New hope for kids with rare kidney cancer: chemo first, then surgery to save kidneys
Disease control CompletedThis study tested giving chemotherapy before surgery to children with Wilms tumor, a rare kidney cancer. The goal was to shrink tumors so surgeons could remove less kidney tissue, helping preserve kidney function. 249 children took part, and the approach aimed to reduce the need …
Phase 3 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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8,000 kidney tumor samples collected to unlock cancer clues
Knowledge-focused CompletedThis completed research study collected and stored tumor tissue, blood, and urine samples from 8,000 children and young adults with kidney tumors. The goal was to help scientists study DNA changes and find biomarkers that could improve understanding of these cancers. No treatment…
Sponsor: Children's Oncology Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC