Restrictive cardiomyopathy
MONDO:0005201A type of heart disorder referring to the inability of the ventricles to fill with blood because the myocardium (heart muscle) stiffens and looses its flexibility. Causes include replacement of the myocardium with scar tissue, abnormal cellular infiltration of the myocardium, or deposition of a substance (e.g., amyloid) in the myocardium.
Also known as: restrictive cardiomyopathy, familial restrictive cardiomyopathy
336 clinical trials for this condition and its sub-types, 18 tagged with Restrictive cardiomyopathy itself.
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Sub-types of Restrictive cardiomyopathy
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Non-familial restrictive cardiomyopathy 0 trials · 252 incl. sub-types
7 sub-types
- AL amyloidosis 93 trials · 99 incl. sub-types Sub-types →
- Wild type ATTR amyloidosis 95 trials
- Hypereosinophilic syndrome 19 trials · 49 incl. sub-types Sub-types →
- Cardiac sarcoidosis 19 trials
- AA amyloidosis 2 trials
- Loeffler endocarditis 0 trials
- Tropical endomyocardial fibrosis 0 trials
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Familial restrictive cardiomyopathy 0 trials · 62 incl. sub-types
10 sub-types
- Glycogen storage disease II 31 trials · 41 incl. sub-types Sub-types →
- Gaucher disease type I 12 trials
- ATTRV122I amyloidosis 7 trials
- Atrial standstill 1 trial Sub-types →
- Idiopathic hypereosinophilic syndrome 1 trial Sub-types →
- Cardiomyopathy, familial restrictive, 1 0 trials
- Cardiomyopathy, familial restrictive, 2 0 trials
- Cardiomyopathy, familial restrictive, 3 0 trials
- Cardiomyopathy, familial restrictive, 6 0 trials
- Dilated cardiomyopathy 1KK 0 trials
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Endomyocardial fibrosis 16 trials
Most studied deeper sub-types
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Can a gene registry unlock the secrets of childhood heart failure?
Knowledge-focused OngoingThis study gathers health information from children under 18 who have cardiomyopathy linked to mutations in the MYBPC3 gene. Researchers aim to map the disease's natural course, identify risk factors, and measure how it affects quality of life. By reviewing past and future medica…
Sponsor: Tenaya Therapeutics • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
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New SPECT method could reveal hidden heart issues in amyloidosis patients
Knowledge-focused OngoingThis study looks at 50 people with TTR amyloid cardiomyopathy, a condition where abnormal proteins build up in the heart. Researchers want to see if a special SPECT scan can measure blood flow in the heart's tiny vessels, which may be impaired even without blocked arteries. Parti…
Sponsor: Centre Hospitalier Régional d'Orléans • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC