Respiratory system disorder
MONDO:0005087A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma.
Also known as: disease of respiratory system, disease or disorder of respiratory system, disorder of respiratory system, respiratory disease, respiratory disorder, respiratory system disease, respiratory system disease or disorder, respiratory system disorder
10848 clinical trials for this condition and its sub-types, 150 tagged with Respiratory system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Respiratory system disorder
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Lower respiratory tract disorder 18 trials · 7,938 incl. sub-types
5 sub-types
- Lung disorder 251 trials · 7,078 incl. sub-types Sub-types →
- Tracheal disorder 6 trials · 1,088 incl. sub-types Sub-types →
- Bronchial disorder 19 trials · 1,010 incl. sub-types Sub-types →
- Pleural disorder 15 trials · 177 incl. sub-types Sub-types →
- Tracheobronchitis 5 trials · 55 incl. sub-types Sub-types →
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Respiratory system cancer 6 trials · 4,516 incl. sub-types
9 sub-types
- Lung cancer 1,207 trials · 3,941 incl. sub-types Sub-types →
- Pharynx cancer 10 trials · 495 incl. sub-types Sub-types →
- Larynx cancer 41 trials · 125 incl. sub-types Sub-types →
- Pleural cancer 9 trials · 83 incl. sub-types Sub-types →
- Bronchus cancer 3 trials · 26 incl. sub-types Sub-types →
- Paranasal sinus cancer 4 trials · 24 incl. sub-types Sub-types →
- Nasal cavity cancer 5 trials · 14 incl. sub-types Sub-types →
- SMARCA4-deficient sarcoma of thorax 8 trials
- Tracheal cancer 0 trials · 1 incl. sub-types Sub-types →
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Respiratory tract neoplasm 32 trials · 4,437 incl. sub-types
8 sub-types
- Lung neoplasm 1,367 trials · 4,039 incl. sub-types Sub-types →
- Nasopharyngeal neoplasm 37 trials · 226 incl. sub-types Sub-types →
- Laryngeal neoplasm 72 trials · 138 incl. sub-types Sub-types →
- Pleural neoplasm 5 trials · 97 incl. sub-types Sub-types →
- Bronchial neoplasm 20 trials · 38 incl. sub-types Sub-types →
- Nasal cavity neoplasm 1 trial · 15 incl. sub-types Sub-types →
- SMARCA4-deficient sarcoma of thorax 8 trials
- Trachea neoplasm 2 trials · 5 incl. sub-types Sub-types →
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Upper respiratory tract disorder 5 trials · 1,848 incl. sub-types
10 sub-types
- Tracheal disorder 6 trials · 1,088 incl. sub-types Sub-types →
- Nasopharyngeal disorder 1 trial · 263 incl. sub-types Sub-types →
- Laryngeal disorder 44 trials · 259 incl. sub-types Sub-types →
- Nasal cavity disorder 3 trials · 224 incl. sub-types Sub-types →
- Pharyngitis 34 trials · 43 incl. sub-types Sub-types →
- Tonsillitis 23 trials · 27 incl. sub-types Sub-types →
- Adenoid hypertrophy 22 trials
- Epiglottitis 1 trial Sub-types →
- Acute laryngopharyngitis 0 trials
- Uvulitis 0 trials
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Respiratory tract infectious disorder 174 trials · 1,330 incl. sub-types
14 sub-types
- Pneumonia 326 trials · 610 incl. sub-types Sub-types →
- Viral respiratory tract infection 47 trials · 564 incl. sub-types Sub-types →
- Fungal lung infectious disease 6 trials · 57 incl. sub-types Sub-types →
- Pulmonary non-tuberculous mycobacterial infection 48 trials
- Streptococcal sore throat 8 trials
- Pleural tuberculosis 7 trials Sub-types →
- Tracheitis 2 trials · 7 incl. sub-types Sub-types →
- Lung abscess 3 trials
- Pneumonic plague 3 trials
- Tuberculous fibrosis of lung 3 trials
- Laryngeal diphtheria 0 trials
- Laryngeal tuberculosis 0 trials
- Nasopharyngeal diphtheria 0 trials
- Silicotuberculosis 0 trials
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Sleep apnea syndrome 214 trials · 600 incl. sub-types
2 sub-types
- Obstructive sleep apnea syndrome 516 trials · 517 incl. sub-types Sub-types →
- Central sleep apnea syndrome 21 trials · 23 incl. sub-types Sub-types →
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Disorder of pharynx 3 trials · 596 incl. sub-types
10 sub-types
- Pharynx cancer 10 trials · 495 incl. sub-types Sub-types →
- Neoplasm of oropharynx 3 trials · 279 incl. sub-types Sub-types →
- Nasopharyngeal disorder 1 trial · 263 incl. sub-types Sub-types →
- Neoplasm of hypopharynx 0 trials · 100 incl. sub-types Sub-types →
- Takayasu arteritis 27 trials
- Tonsillitis 23 trials · 27 incl. sub-types Sub-types →
- Tonsil neoplasm 0 trials · 8 incl. sub-types Sub-types →
- Peritonsillar abscess 4 trials
- Epiglottitis 1 trial Sub-types →
- Oropharyngeal anthrax 0 trials
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Cystic fibrosis 283 trials
1 sub-type
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Allergic respiratory disease 2 trials · 218 incl. sub-types
4 sub-types
- Allergic rhinitis 96 trials · 140 incl. sub-types Sub-types →
- Allergic asthma 41 trials Sub-types →
- Hypersensitivity pneumonitis 25 trials · 30 incl. sub-types Sub-types →
- Allergic bronchopulmonary aspergillosis 15 trials Sub-types →
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Paranasal sinus disorder 12 trials · 162 incl. sub-types
7 sub-types
- Sinusitis 44 trials · 130 incl. sub-types Sub-types →
- Paranasal sinus neoplasm 5 trials · 29 incl. sub-types Sub-types →
- Maxillary sinus cholesteatoma 0 trials
- Polyp of ethmoidal sinus 0 trials
- Polyp of frontal sinus 0 trials
- Polyp of maxillary sinus 0 trials
- Polyp of sphenoidal sinus 0 trials
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Perinatal asphyxia 152 trials
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Pulmonary tuberculosis 107 trials · 110 incl. sub-types
3 sub-types
- Tuberculous fibrosis of lung 3 trials
- Primary pulmonary tuberculosis 0 trials
- Silicotuberculosis 0 trials
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Bronchopulmonary dysplasia 96 trials
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Diaphragm disorder 27 trials · 91 incl. sub-types
5 sub-types
- Congenital diaphragmatic hernia 45 trials Sub-types →
- Respiratory paralysis 20 trials
- Diaphragmatic eventration 3 trials
- Diaphragmatic malformation 1 trial
- Diaphragmitis 0 trials
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Altitude sickness 54 trials · 56 incl. sub-types
2 sub-types
- Acute mountain sickness 7 trials
- Chronic mountain sickness 3 trials
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Alpha 1-antitrypsin deficiency 44 trials
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Pertussis 39 trials
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Primary ciliary dyskinesia 34 trials
59 sub-types
- Primary ciliary dyskinesia 1 6 trials
- CFAP46-related primary ciliary dyskinesia 0 trials
- Stromme syndrome 0 trials
- Ciliary discoordination due to random ciliary orientation 0 trials
- Ciliary dyskinesia with defective radial spokes 0 trials
- Ciliary dyskinesia with excessively long cilia 0 trials
- Ciliary dyskinesia with transposition of ciliary microtubules 0 trials
- Ciliary dyskinesia, primary, 36, X-linked 0 trials
- Ciliary dyskinesia, primary, 37 0 trials
- Ciliary dyskinesia, primary, 38 0 trials
- Ciliary dyskinesia, primary, 39 0 trials
- Ciliary dyskinesia, primary, 40 0 trials
- Ciliary dyskinesia, primary, 41 0 trials
- Ciliary dyskinesia, primary, 42 0 trials
- Ciliary dyskinesia, primary, 43 0 trials
- Ciliary dyskinesia, primary, 44 0 trials
- Ciliary dyskinesia, primary, 45 0 trials
- Ciliary dyskinesia, primary, 46 0 trials
- Ciliary dyskinesia, primary, 47, and lissencephaly 0 trials
- Ciliary dyskinesia, primary, 48, without situs inversus 0 trials
- Ciliary dyskinesia, primary, 49, without situs inversus 0 trials
- Ciliary dyskinesia, primary, 50 0 trials
- Ciliary dyskinesia, primary, 51 0 trials
- Ciliary dyskinesia, primary, 52 0 trials
- Ciliary dyskinesia, primary, 53 0 trials
- Ciliary dyskinesia, primary, 54 0 trials
- Primary ciliary dyskinesia 10 0 trials
- Primary ciliary dyskinesia 11 0 trials
- Primary ciliary dyskinesia 12 0 trials
- Primary ciliary dyskinesia 13 0 trials
- Primary ciliary dyskinesia 14 0 trials
- Primary ciliary dyskinesia 15 0 trials
- Primary ciliary dyskinesia 16 0 trials
- Primary ciliary dyskinesia 17 0 trials
- Primary ciliary dyskinesia 18 0 trials
- Primary ciliary dyskinesia 19 0 trials
- Primary ciliary dyskinesia 2 0 trials
- Primary ciliary dyskinesia 20 0 trials
- Primary ciliary dyskinesia 21 0 trials
- Primary ciliary dyskinesia 22 0 trials
- Primary ciliary dyskinesia 23 0 trials
- Primary ciliary dyskinesia 24 0 trials
- Primary ciliary dyskinesia 25 0 trials
- Primary ciliary dyskinesia 26 0 trials
- Primary ciliary dyskinesia 27 0 trials
- Primary ciliary dyskinesia 28 0 trials
- Primary ciliary dyskinesia 29 0 trials
- Primary ciliary dyskinesia 3 0 trials
- Primary ciliary dyskinesia 30 0 trials
- Primary ciliary dyskinesia 32 0 trials
- Primary ciliary dyskinesia 33 0 trials
- Primary ciliary dyskinesia 34 0 trials
- Primary ciliary dyskinesia 35 0 trials
- Primary ciliary dyskinesia 4 0 trials
- Primary ciliary dyskinesia 5 0 trials
- Primary ciliary dyskinesia 6 0 trials
- Primary ciliary dyskinesia 7 0 trials
- Primary ciliary dyskinesia 8 0 trials
- Primary ciliary dyskinesia 9 0 trials
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Severe acute respiratory syndrome 30 trials
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Infantile apnea 5 trials · 22 incl. sub-types
1 sub-type
- Apnea of prematurity 20 trials
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Recurrent respiratory papillomatosis 8 trials · 9 incl. sub-types
1 sub-type
- Laryngeal papillomatosis 1 trial
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Respiratory system benign neoplasm 1 trial · 8 incl. sub-types
15 sub-types
- Benign laryngeal neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Benign neoplasm of trachea 0 trials · 2 incl. sub-types Sub-types →
- Lung benign neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Benign neoplasm of nasal cavity 1 trial Sub-types →
- Benign neoplasm of ethmoidal sinus 0 trials Sub-types →
- Benign neoplasm of frontal sinus 0 trials Sub-types →
- Benign neoplasm of hypopharynx 0 trials Sub-types →
- Benign neoplasm of maxillary sinus 0 trials Sub-types →
- Benign neoplasm of nasopharynx 0 trials
- Benign neoplasm of oropharynx 0 trials
- Benign neoplasm of pleura 0 trials Sub-types →
- Benign neoplasm of sphenoidal sinus 0 trials Sub-types →
- Benign neoplasm of tonsil 0 trials Sub-types →
- Endobronchial lipoma 0 trials
- Paranasal sinus Schneiderian papilloma 0 trials Sub-types →
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Respiratory or thoracic malformation 0 trials · 8 incl. sub-types
1 sub-type
- Thoracic malformation 1 trial · 8 incl. sub-types Sub-types →
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Pulmonary hypoplasia 7 trials
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Reactive airway disease 5 trials
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2 sub-types
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5 sub-types
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Young syndrome 2 trials
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Diffuse alveolar hemorrhage 2 trials
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Plastic bronchitis 2 trials
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Middle East respiratory syndrome 1 trial
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Bronchogenic cyst 1 trial
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3 sub-types
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16q24.1 microdeletion syndrome 0 trials
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IgG4-related mediastinitis 0 trials
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Mounier-Kuhn syndrome 0 trials
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Siegler-Brewer-Carey syndrome 0 trials
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Williams-Campbell syndrome 0 trials
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Acinar dysplasia 0 trials
3 sub-types
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Bronchiectasis and nasal polyposis 0 trials
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Congenital bronchobiliary fistula 0 trials
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Eosinophilic granuloma 0 trials
1 sub-type
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Isolated left bronchial isomerism 0 trials
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Laryngo-onycho-cutaneous syndrome 0 trials
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Mucopolysaccharidosis-plus syndrome 0 trials
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Pulmonary agenesis 0 trials
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Staphylococcal necrotizing pneumonia 0 trials
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Tracheal agenesis 0 trials
Most studied deeper sub-types
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Placenta cells tested as COVID fighter – but trial stopped early
Disease control Stopped earlyThis early-phase trial tested a new therapy called CYNK-001, which uses natural killer cells from the placenta to fight COVID-19. It enrolled only 7 adults with moderate COVID-19. The study was terminated early, so we have limited information on safety and effectiveness.
Phase 1/2 • Sponsor: Celularity Incorporated • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Targeted pill shows promise for rare lung cancer, but trial stopped early
Disease control Stopped earlyThis phase 3 study tested a new drug called pralsetinib against standard chemotherapy for people with a specific type of advanced lung cancer that has a RET gene fusion. The goal was to see if pralsetinib could better delay cancer growth. The trial was terminated early, so full r…
Phase 3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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New inhaled drug aimed at stubborn lung infection shows promise, but trial halted early
Disease control Stopped earlyThis phase 3 study tested an inhaled form of the antibiotic clofazimine added to standard therapy for people with MAC lung disease that did not respond to previous treatment. The goal was to see if the drug could clear the infection from sputum cultures and improve quality of lif…
Phase 3 • Sponsor: Mannkind Corporation • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Experimental asthma drug briquilimab fails to reach Late-Stage testing
Disease control Stopped earlyThis Phase 1 trial tested a single dose of briquilimab in 17 adults with mild-to-moderate allergic asthma to see if it was safe and could reduce asthma attacks triggered by allergens. The study was terminated early, meaning it did not continue as planned. The main goal was to che…
Phase 1 • Sponsor: Jasper Therapeutics, Inc. • Aim: Disease control
Last updated Jun 26, 2026 18:40 UTC
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Inhaler trial for Kids' lung decline after transplant ends early
Disease control Stopped earlyThis phase 3 trial tested whether a combination inhaler (fluticasone and salmeterol) could improve lung function in children aged 6–17 who had a drop in breathing capacity after a stem cell transplant. The study aimed to prevent bronchiolitis obliterans, a serious lung complicati…
Phase 3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 26, 2026 17:44 UTC