Renal tubular acidosis

MONDO:0001909

A group of genetic disorders of the kidney tubules characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic acidosis. Defective renal acidification of urine (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as hypokalemia, hypercalcinuria with nephrolithiasis and nephrocalcinosis, and rickets.

2 clinical trials for this condition and its sub-types, 2 tagged with Renal tubular acidosis itself.

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Where it sits in the disease tree

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Part of

↑ Renal tubule disorder (47) ↑ Acidosis disorder (23) ↑ Renal tubular transport disease (17)

Sub-types of Renal tubular acidosis

Hyperkalemic renal tubular acidosis 0 trials
Neuroaxonal dystrophy renal tubular acidosis 0 trials
Proximal renal tubular acidosis 0 trials
2 sub-types
- Autosomal dominant proximal renal tubular acidosis 0 trials
- Autosomal recessive proximal renal tubular acidosis 0 trials
Renal tubular acidosis 3 0 trials
Renal tubular acidosis, distal, 3, with or without sensorineural hearing loss 0 trials

Including sub-types (2) Tagged with Renal tubular acidosis (2)

Not yet finished but already full! 1 Terminated 1

Kidney acidosis drug study pulled before it began

Disease control Cancelled

This study was designed to check the long-term safety and effectiveness of a drug called ADV7103 in people with primary distal renal tubular acidosis, a rare kidney problem that leads to too much acid in the blood. It planned to include people who had been in an earlier study, as…

Phase 3 • Sponsor: Advicenne Pharma • Aim: Disease control

Last updated Jun 27, 2026 09:03 UTC

Renal tubular acidosis

Where it sits in the disease tree

Kidney acidosis drug study pulled before it began