Refractive error
MONDO:0004892A defect in the focusing of light on the retina as in astigmatism, myopia, or hyperopia.
399 clinical trials for this condition and its sub-types, 82 tagged with Refractive error itself.
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Sub-types of Refractive error
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Myopia 258 trials · 273 incl. sub-types
30 sub-types
- Degenerative myopia 38 trials
- Myopia, high, with cataract and vitreoretinal degeneration 1 trial
- Myopia 1, X-linked 0 trials
- Myopia 10 0 trials
- Myopia 11, autosomal dominant 0 trials
- Myopia 12, autosomal dominant 0 trials
- Myopia 13, X-linked 0 trials
- Myopia 14 0 trials
- Myopia 15, autosomal dominant 0 trials
- Myopia 16, autosomal dominant 0 trials
- Myopia 17, autosomal dominant 0 trials
- Myopia 18, autosomal recessive 0 trials
- Myopia 19, autosomal dominant 0 trials
- Myopia 2, autosomal dominant 0 trials
- Myopia 20, autosomal dominant 0 trials
- Myopia 21, autosomal dominant 0 trials
- Myopia 22, autosomal dominant 0 trials
- Myopia 23, autosomal recessive 0 trials
- Myopia 24, autosomal dominant 0 trials
- Myopia 25, autosomal dominant 0 trials
- Myopia 26, X-linked, female-limited 0 trials
- Myopia 27 0 trials
- Myopia 28, autosomal recessive 0 trials
- Myopia 3, autosomal dominant 0 trials
- Myopia 5, autosomal dominant 0 trials
- Myopia 6 0 trials
- Myopia 7 0 trials
- Myopia 8 0 trials
- Myopia 9 0 trials
- Schizophrenia 16 0 trials
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Astigmatism 77 trials · 80 incl. sub-types
2 sub-types
- Irregular astigmatism 5 trials
- Regular astigmatism 2 trials
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Presbyopia 62 trials
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Hyperopia 27 trials
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Anisometropia 7 trials
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Aniseikonia 0 trials
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Transient refractive change 0 trials
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Donated corneal tissue eyed as fix for Post-LASIK farsightedness
Disease control By invitation onlyMany people who have LASIK still need glasses for leftover farsightedness. Researchers are testing whether implanting a thin piece of donated corneal tissue, shaped by ReLex Smile surgery, can improve vision. The trial enrolls 60 young adults with residual farsightedness after LA…
Sponsor: Eye Hospital Pristina Kosovo • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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New glasses aim to halt adult nearsightedness
Disease control OngoingThis study tests whether Essilor Stellest spectacle lenses can slow the progression of nearsightedness (myopia) in adults aged 18 to 40. Each participant wears a Stellest lens in one eye and a standard lens in the other, allowing direct comparison. The trial measures changes in e…
Sponsor: University of Ulster • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Surfer's eye surgery may sharpen vision by reshaping cornea
Disease control By invitation onlyThis study looks at how removing a pterygium (a fleshy growth on the eye) and replacing it with a small piece of the patient's own eye tissue changes the shape of the cornea. Researchers will measure the cornea's curve before and one month after surgery in 130 adults aged 30 to 7…
Sponsor: Mughal Eye Trust Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New contact lens trial aims to stop worsening eyesight in children
Disease control OngoingThis study tests whether NaturalVue multifocal contact lenses can slow the progression of myopia (nearsightedness) in children aged 7 to 12. Over three years, 144 kids will wear either standard single-vision lenses or the multifocal lenses. Researchers will measure changes in the…
Sponsor: Visioneering Technologies, Inc • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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AI eye test: could a computer replace your eye doctor?
Diagnosis By invitation onlyThis study compares a new AI system, called AEYE, against a human eye doctor in diagnosing keratoconus and deciding who is eligible for laser vision correction. The AI analyzes patient history, eye scans, and other data to make its recommendations. Researchers will check if the A…
Sponsor: Hazem Yassin Clinics • Aim: Diagnosis
Last updated Jun 26, 2026 17:00 UTC
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A simple fix for myopia could change education for millions
Prevention OngoingThis trial tests whether giving free glasses to short-sighted middle school children in rural China helps more of them continue to academic high school. Researchers will randomly assign 111 schools to either provide glasses with teacher support or just give prescriptions. The mai…
Sponsor: Queen's University, Belfast • Aim: Prevention
Last updated Sep 10, 2026 00:00 UTC
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Can a daily vitamin and sunshine curb Kids' nearsightedness?
Prevention CancelledThis study tests whether taking vitamin B2 (riboflavin) daily and spending time outdoors in sunlight can slow the progression of myopia (nearsightedness) in children aged 6 to 12. Participants will be randomly assigned to receive different doses of riboflavin or a placebo, and al…
Phase 2 • Sponsor: University of Missouri-Columbia • Aim: Prevention
Last updated Aug 26, 2026 00:00 UTC
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Could a tiny corneal implant replace reading glasses?
Symptom relief OngoingThis study tests a new device called CorVision, a tiny lens made from collagen that is placed inside the cornea to improve near vision in people with presbyopia (age-related difficulty seeing up close). 110 adults aged 40-65 will receive the implant in one eye through a minimally…
Sponsor: LinkoCare Life Sciences AB • Aim: Symptom relief
Last updated Jun 26, 2026 12:33 UTC
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New study aims to tackle vision problems in upper manhattan
Knowledge-focused CancelledThis study aims to help adults aged 40 and older in Upper Manhattan get better eye care. It will offer free eye screenings at local health centers and senior centers, and provide support like scheduling appointments and transportation. The goal is to see if this extra help leads …
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC