Rectal disorder
MONDO:0001593A disease that involves the rectum.
Also known as: disease of rectum, disease or disorder of rectum, disorder of rectum, rectal disorder, rectum disease, rectum disease or disorder
793 clinical trials for this condition and its sub-types, 22 tagged with Rectal disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Rectal disorder
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Rectal neoplasm 433 trials · 690 incl. sub-types
4 sub-types
- Rectal cancer 433 trials · 633 incl. sub-types Sub-types →
- Epithelial neoplasm of rectum 0 trials · 398 incl. sub-types Sub-types →
- Anus neoplasm 87 trials · 140 incl. sub-types Sub-types →
- Benign neoplasm of rectum 2 trials Sub-types →
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Anus disorder 3 trials · 171 incl. sub-types
7 sub-types
- Anus neoplasm 87 trials · 140 incl. sub-types Sub-types →
- Proctitis 2 trials · 21 incl. sub-types Sub-types →
- Imperforate anus 6 trials
- Levator syndrome 1 trial
- Anal polyp 0 trials Sub-types →
- Anal spasm 0 trials
- Anorectal stricture 0 trials
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Anal fistula 57 trials
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Rectal prolapse 6 trials
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Polyp of rectum 3 trials
2 sub-types
- Anal polyp 0 trials Sub-types →
- Rectal hyperplastic polyp 0 trials
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Ulcer of anus and rectum 0 trials
Most studied deeper sub-types
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Drain or no drain? landmark trial settles debate after rectal cancer surgery
Disease control CompletedThis study tested whether placing a temporary drain in the pelvis after rectal cancer surgery reduces the risk of serious infections like leaks or abscesses. About 500 patients were randomly assigned to receive a drain or not. The main goal was to see if drainage lowered pelvic s…
Phase 3 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New combo attack on rectal cancer: chemo plus targeted surgery shows promise
Disease control CompletedThis study looked at 180 people with rectal cancer that had spread to lymph nodes in the pelvis. One group received a three-drug chemotherapy regimen (FOLFOXIRI) followed by surgery to remove the affected lymph nodes. The other group got standard chemoradiotherapy before surgery.…
Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Which surgery works best for hirschsprung disease? new study compares swenson and soave techniques
Disease control CompletedThis study looked at 20 children with Hirschsprung disease, a condition where part of the bowel lacks nerve cells, causing severe constipation. Researchers compared two surgical methods—Swenson and Soave—to see which one had shorter operation time and better daily bowel movements…
Sponsor: Ahmed Aouf • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Blood test may spot colon cancer early, study shows
Diagnosis CompletedThis study tested a new blood test designed to find colorectal cancer early in people at average risk. Nearly 49,000 adults aged 45-85 gave a blood sample before their routine colonoscopy. The goal was to see how well the blood test could detect cancer and advanced growths compar…
Sponsor: Freenome Holdings Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC
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Spina bifida bowel troubles: scientists probe nerve and gut lining
Knowledge-focused CompletedThis study looked at 36 adults with spina bifida to understand why they often have bowel issues. Researchers took small tissue samples from the colon during a routine scope and measured how the rectum works. The goal was to see if nerve damage affects the gut's lining and nerves,…
Sponsor: Rennes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Nurse coordinator may boost recovery plan compliance in colorectal surgery
Knowledge-focused CompletedThis study tested whether having a nurse coordinator (NEC) helps patients follow the Enhanced Recovery After Surgery (ERAS) program after colorectal surgery. Over 200 patients from multiple hospitals took part, with one group having the nurse and the other not. The goal was to se…
Sponsor: Hospital Universitari de Bellvitge • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:01 UTC