Recessive X-linked ichthyosis
MONDO:0010622A genodermatosis belonging to the Mendelian Disorders of Cornification (MeDOC) and characterized by generalized hyperkeratosis and scaling of the skin.
Also known as: Ichthyosis, X Linked, RXLI, X-linked ichthyosis, X-linked recessive ichthyosis, XLI, ichthyosis (disease), X-linked, ichthyosis , X-linked, X-linked recessive, recessive X-linked ichthyosis
4 clinical trials for this condition and its sub-types, 2 tagged with Recessive X-linked ichthyosis itself.
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Sub-types of Recessive X-linked ichthyosis
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New ointment shows promise for rare skin condition
Disease control CompletedThis Phase 3 study tested an ointment called TMB-001 in 153 people aged 6 and older with X-linked or ARCI ichthyosis, conditions that cause dry, scaly, and cracked skin. Participants applied the ointment or a placebo daily for 12 weeks, with some continuing for maintenance. The g…
Phase 3 • Sponsor: LEO Pharma • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New ointment shows promise for rare skin scaling disease
Symptom relief CompletedThis study tested two strengths of a topical isotretinoin ointment (TMB-001) in 34 people aged 9 and older with congenital ichthyosis, a rare genetic skin condition causing severe scaling. The main goal was to see if the ointment could reduce scaling by at least 50% compared to a…
Phase 2 • Sponsor: LEO Pharma • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC