Radiation injury

Researchers are testing a combination of two radiation techniques for men with intermediate or high risk prostate cancer. Participants receive a shortened course of external beam radiation followed by a single high-dose brachytherapy boost, with optional hormone therapy. The tria…

This trial tests whether proton therapy, a more precise form of radiation, causes fewer long-term bowel side effects than standard photon therapy in men with high-risk prostate cancer. Participants receive the same radiation dose and schedule, but one group gets protons and the o…

This phase 3 trial compares a new, shorter course of radiation (ultra-hypofractionated) to the standard longer course for men with prostate cancer that has spread to lymph nodes. Both groups also receive a brachytherapy boost and hormone therapy. The study aims to see if the shor…

Researchers are examining whether the Gleason score, prostate-specific antigen (PSA) level, and clinical stage can predict treatment failure, death, and quality of life in men who received radiation therapy for localized prostate cancer. The study reviews medical records and ques…

This study is looking at people hospitalized for a heart attack (STEMI or NSTEMI) who undergo a procedure to open blocked heart arteries, called percutaneous coronary intervention (PCI) or angioplasty. It compares two groups: those having a standard (non-complex) PCI and those ha…

This study follows breast cancer patients who have had curative surgery and are receiving hypofractionated radiation therapy—shorter treatment courses lasting one to three weeks. Researchers will track changes in breast skin, fibrosis, cosmetic appearance, and patient-reported ou…

This study tests a tool that helps patients with lung cancer or lung metastases work with their doctor to choose the right radiation dose. The tool is designed for tumors very close to the chest wall. The goal is to see if using this tool leads to better shared decision-making an…

This study follows about 190,000 Korean radiation workers to see if low-dose radiation exposure over time increases the risk of cancer and other diseases. Researchers will link national health records to track health outcomes. The goal is to better understand the long-term effect…

This study looks at dental and jaw problems in children who had proton beam therapy for head and neck cancer. Researchers will survey survivors and review dental records to see how often these side effects occur and how they relate to radiation dose. The goal is to gather informa…

This study tracks 221 people with stage II or III lung cancer to see how chemoradiation therapy affects their heart health. Participants undergo heart scans, blood tests, and quality-of-life surveys before, during, and for at least two years after treatment. The goal is to better…