Pulmonary valve insufficiency
MONDO:0001927Dysfunction of the pulmonary valve characterized by incomplete valve closure.
Also known as: pulmonary regurgitation, pulmonary valve regurgitation, pulmonary valvular regurgitation, regurgitation, pulmonary
50 clinical trials for this condition and its sub-types, 19 tagged with Pulmonary valve insufficiency itself.
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New heart valve trial offers hope for patients with rare congenital defects
Disease control Recruiting nowThis study is testing a new heart valve (SAPIEN 3) in 108 people who have a dysfunctional right ventricle outflow tract (RVOT) due to a congenital heart defect or a previous valve replacement. The goal is to see if the valve is safe and effective at improving blood flow and reduc…
Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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New heart valve study aims to fix leaky valve without Open-Heart surgery
Disease control Recruiting nowThis study is tracking 80 people with severe pulmonary valve regurgitation (a leaky heart valve) who receive the Harmony Transcatheter Pulmonary Valve. The valve is placed through a catheter, avoiding open-heart surgery. Researchers will check if the valve works well and stays in…
Sponsor: Medtronic Cardiovascular • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Grow your own heart valve: first human trial launches
Disease control Recruiting nowThis study tests a new type of heart valve made from a patient's own tissue to treat a leaky pulmonary valve. Seven adults will receive the valve to see if it is safe and works well in the short term. The valve is designed to grow with the patient, potentially reducing the need f…
Sponsor: Charite University, Berlin, Germany • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New registry monitors heart valve patients for better outcomes
Knowledge-focused Recruiting nowThis study follows 200 adults who have had or will have a procedure to fix a leaky or narrowed valve in the right side of the heart. Researchers track survival, unplanned hospital stays, and heart function using blood tests and ultrasound. The goal is to learn which treatments wo…
Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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10,000 patients join quest to unlock heart valve disease secrets
Knowledge-focused Recruiting nowThis study is following 10,000 adults with heart valve disease to see how their condition changes over time. Researchers will use scans, blood tests, and health records to track progression and the effects of treatments like surgery or medication. The goal is to better predict ou…
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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New study aims to improve heart testing accuracy for valve disease
Knowledge-focused Recruiting nowThis study involves 70 adults with severe heart valve disease who are already scheduled for a routine heart catheterization. Researchers will use special catheters to measure how well the right side of the heart works with the lungs. The goal is to see if simpler, non-invasive te…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:24 UTC