Proliferative vitreoretinopathy

MONDO:0700115

Vitreoretinal membrane shrinkage or contraction secondary to the proliferation of primarily retinal pigment epithelial cells and glial cells, particularly fibrous astrocytes, followed by membrane formation. The formation of fibrillar collagen and cellular proliferation appear to be the basis for the contractile properties of the epiretinal and vitreous membranes.

20 clinical trials for this condition and its sub-types, 7 tagged with Proliferative vitreoretinopathy itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Retinal disorder (959)

Sub-types of Proliferative vitreoretinopathy

CAPN5-related vitreoretinopathy 0 trials

Including sub-types (20) Tagged with Proliferative vitreoretinopathy (7)

Trials to join now! 1 Not yet recruiting 2 Not yet finished but already full! 2 Completed 2

Could a simple eye drop stop blindness after retinal detachment?

Prevention Recruiting now

This study tests whether netarsudil eye drops can prevent proliferative vitreoretinopathy (PVR), a scarring condition that can cause retinal detachment surgery to fail. Researchers will check how much of the drug reaches the back of the eye and whether it is safe. The trial enrol…

Phase 1/2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Prevention

Last updated Jun 27, 2026 07:55 UTC

Proliferative vitreoretinopathy

Where it sits in the disease tree

Could a simple eye drop stop blindness after retinal detachment?