Proliferative vitreoretinopathy
MONDO:0700115Vitreoretinal membrane shrinkage or contraction secondary to the proliferation of primarily retinal pigment epithelial cells and glial cells, particularly fibrous astrocytes, followed by membrane formation. The formation of fibrillar collagen and cellular proliferation appear to be the basis for the contractile properties of the epiretinal and vitreous membranes.
20 clinical trials for this condition and its sub-types, 7 tagged with Proliferative vitreoretinopathy itself.
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Sub-types of Proliferative vitreoretinopathy
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CAPN5-related vitreoretinopathy 0 trials
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Can a steroid injection tame the inflammation behind retinal detachment?
Disease control CompletedThis trial tests whether a steroid injection given about a week before surgery can reduce harmful inflammation and scarring in people with retinal detachment. Participants are randomly assigned to receive either the injection plus standard surgery or surgery alone. The study meas…
Sponsor: Anggun Rama Yudantha • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
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Eye drops before surgery may tame inflammation in retinal detachment
Disease control CompletedThis study tested whether nepafenac 0.1% eye drops, given before surgery, can lower inflammation in people with retinal detachment. Sixty-one adults used the drops or a placebo for five days before surgery. Researchers measured inflammatory markers in the eye fluid. The goal is t…
Phase 4 • Sponsor: Indonesia University • Aim: Disease control
Last updated Jun 26, 2026 15:21 UTC