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Progressive supranuclear palsy-corticobasal syndrome

MONDO:0016563

PSP-corticobasal syndrome (PSP-CBS) is an atypical variant of progressive supranuclear palsy (PSP), a rare late-onset neurodegenerative disease.

Also known as: PSP-CBS, PSP-corticobasal syndrome

14 clinical trials for this condition and its sub-types, 1 tagged with Progressive supranuclear palsy-corticobasal syndrome itself.

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Where it sits in the disease tree

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Part of

↑ Atypical progressive supranuclear palsy syndrome (4)

Including sub-types (14) Tagged with Progressive supranuclear palsy-corticobasal syndrome (1)

Could a common drug slow down this rare brain disease?

Disease control Completed

This phase 2 trial tests whether glycerol phenylbutyrate (GPB) can slow corticobasal syndrome (CBS), a rare and fast-progressing brain disease. 32 adults with CBS will receive either GPB or a placebo for 26 weeks. The main goal is to see if GPB lowers levels of a nerve damage mar…

Phase 2 • Sponsor: Technical University of Munich • Aim: Disease control

Last updated Sep 13, 2026 00:00 UTC