Progressive external ophthalmoplegia
MONDO:0005181A mitochondrial myopathy characterized by slowly progressive paralysis of the levator palpebrae, orbicularis oculi, and extraocular muscles. Ragged-red fibers and atrophy are found on muscle biopsy. Familial and sporadic forms may occur. Disease onset is usually in the first or second decade of life, and the illness slowly progresses until usually all ocular motility is lost. (From Adams et al., Principles of Neurology, 6th ed, p1422)
Also known as: chronic progressive external ophthalmoplegia [ambiguous], progressive external ophthalmoplegia, chronic progressive external ophthalmoplegia
24 clinical trials for this condition and its sub-types, 4 tagged with Progressive external ophthalmoplegia itself.
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Sub-types of Progressive external ophthalmoplegia
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Kearns-Sayre syndrome 5 trials
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Progressive external ophthalmoplegia with mitochondrial DNA deletions 0 trials · 2 incl. sub-types
8 sub-types
- Autosomal dominant progressive external ophthalmoplegia 1 trial · 2 incl. sub-types Sub-types →
- Mitochondrial DNA deletion syndrome with progressive myopathy 0 trials
- Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 1 0 trials
- Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2 0 trials
- Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 3 0 trials
- Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 4 0 trials
- Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 5 0 trials
- Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 6 0 trials