Primary hyperparathyroidism
MONDO:0010837Hyperfunction of the parathyroid glands resulting in the overproduction of parathyroid hormone. It is caused by parathyroid adenoma, parathyroid hyperplasia, parathyroid carcinoma, and multiple endocrine neoplasia. It is associated with hypercalcemia and hypophosphatemia. Signs and symptoms include weakness, fatigue, nausea, vomiting, constipation, depression, bone pain, osteoporosis, cystic bone lesions, and kidney stones.
Also known as: primary hyperparathyroidism, primary hyperparathyroidism (disease)
58 clinical trials for this condition and its sub-types, 23 tagged with Primary hyperparathyroidism itself.
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Sub-types of Primary hyperparathyroidism
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Familial primary hyperparathyroidism 1 trial · 35 incl. sub-types
5 sub-types
Most studied deeper sub-types
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Can a new infrared camera help surgeons spot nerves and bile ducts?
Knowledge-focused By invitation onlyThis trial is testing an investigational imaging device that uses shortwave infrared light to help surgeons see important structures like nerves, ureters, and bile ducts during surgery. The study involves adults aged 18 and older who are undergoing certain surgical procedures, su…
Sponsor: Cision Vision, Inc. • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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Parathyroid surgery may help control diabetes, study suggests
Knowledge-focused OngoingThis study looks at whether removing overactive parathyroid glands (parathyroidectomy) can improve blood sugar control in people who also have type 2 diabetes. Researchers will compare 80 patients who have surgery with those who do not, measuring changes in blood sugar and bone h…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC