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Primary hyperoxaluria type 3

MONDO:0013327

Primary hyperoxaluria type 3 (PH3) is a disorder of glyoxylate metabolism that can be asymptomatic or characterized by oxalate nephrolithiasis.

Also known as: HOGA1 primary hyperoxaluria, primary hyperoxaluria caused by mutation in HOGA1, primary hyperoxaluria type III, HP3, PH III, hyperoxaluria, primary, type 3, hyperoxaluria, primary, type III

2 clinical trials for this condition and its sub-types, 2 tagged with Primary hyperoxaluria type 3 itself.

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↑ Primary hyperoxaluria (17)

Including sub-types (2) Tagged with Primary hyperoxaluria type 3 (2)

Not yet finished but already full! 1 Completed 1

Promising drug may protect kidneys in kids with rare oxalate disorder

Disease control Completed

This study tested a monthly injection called nedosiran in 27 children from birth to 11 years old with primary hyperoxaluria, a rare condition that causes harmful oxalate buildup and kidney damage. The goal was to see if the drug safely lowers oxalate levels in the urine. Early re…

Phase 2 • Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company • Aim: Disease control

Last updated Jun 27, 2026 12:08 UTC

Primary hyperoxaluria type 3

Where it sits in the disease tree

Promising drug may protect kidneys in kids with rare oxalate disorder