Primary cutaneous diffuse large B-cell lymphoma, Leg type
MONDO:0006383An aggressive primary cutaneous B-cell lymphoma, usually involving the lower leg. It is composed of a generally monotonous proliferation of immunoblasts, or less frequently centroblasts, with few admixed reactive cells. This type of lymphoma occurs most often in elderly women who present with rapidly growing tumors, usually on one or both legs. Dissemination to extracutaneous sites is frequent. Treatment with combination chemotherapy is usually required.
Also known as: PCDLBCL,LT, primary cutaneous diffuse large B-cell lymphoma, Leg type
2005 clinical trials for this condition and its sub-types, 7 tagged with Primary cutaneous diffuse large B-cell lymphoma, Leg type itself.
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New drug SGR-1505 enters early human testing for blood cancers
Disease control Recruiting nowThis early-phase trial tests a new drug, SGR-1505, in about 98 adults with various B-cell blood cancers (like lymphoma or leukemia) that have not responded to other treatments. The main goals are to find the safest dose and understand side effects. Participants will receive the d…
Phase 1 • Sponsor: Schrödinger, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New spinal fluid test could spot hidden lymphoma in the brain
Knowledge-focused Recruiting nowThis study is testing a new spinal fluid test that looks for tumor DNA in people with aggressive B-cell lymphoma who are at high risk for the cancer spreading to the brain. Researchers want to see how often this test finds signs of lymphoma that standard tests miss. About 50 part…
Phase 2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC