Pouchitis
MONDO:0005312Acute inflammation in the intestinal mucosa of the continent ileal reservoir (or pouch) in patients who have undergone ileostomy and restorative proctocolectomy (proctocolectomy, restorative).
23 clinical trials for this condition and its sub-types, 18 tagged with Pouchitis itself.
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New COVID-19 booster studied for vulnerable patients
Vaccine CompletedThis study tested a Novavax COVID-19 booster vaccine in 21 people with weakened immune systems due to inflammatory bowel disease or organ transplants. The goal was to see if the booster improved antibody levels and immune protection against COVID-19. Participants had already rece…
Phase 2 • Sponsor: University of Wisconsin, Madison • Aim: Vaccine
Last updated Jun 27, 2026 07:55 UTC
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Can a stool transplant calm an inflamed pouch?
Disease control CompletedThis study tests whether giving healthy donor stool through an enema once a week for six weeks can help people with active pouchitis—a condition where the surgically created intestinal pouch becomes inflamed. Half the participants receive the real transplant, while the other half…
Phase 2 • Sponsor: McMaster University • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Real-World study confirms kynteles safety for IBD patients
Disease control CompletedThis study monitored 688 people in South Korea with ulcerative colitis, Crohn's disease, or pouchitis who were treated with Kynteles (vedolizumab) as part of their normal care. The main goal was to track side effects, and researchers also looked at how many patients saw symptom i…
Sponsor: Takeda • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Sound waves vs. scope: a gentler way to spot pouch inflammation?
Diagnosis CompletedThis study tests whether intestinal ultrasound can accurately detect pouchitis—inflammation of the internal pouch created after ulcerative colitis surgery. Adults who have had this surgery will receive an ultrasound, and the results will be compared to the standard pouchoscopy wi…
Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Aug 14, 2026 00:00 UTC