Postpoliomyelitis syndrome
MONDO:0017416Postpoliomyelitis syndrome (PPS) is a neurologic disorder characterized by the development of new neuromuscular symptoms such as progressive muscular weakness or abnormal muscle fatigability occurring in survivors of the acute paralytic form of poliomyelitis, 15-40 years after recovery from the disease, and that is unexplained by other medical causes. Other manifestations that can occur gradually include generalized fatigue, muscle atrophy, muscle and joint pain, intolerance to cold, and difficulties sleeping, swallowing or breathing.
Also known as: Post Polio Syndrome, postpolio sequelae, postpolio syndrome, postpoliomyelitic syndrome, postpoliomyelitis sequelae, postpoliomyelitis syndrome, polio late effects, post polio syndrome
26 clinical trials for this condition and its sub-types, 11 tagged with Postpoliomyelitis syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
-
New powered brace aims to restore mobility for leg weakness patients
Symptom relief Recruiting nowThis study tests a powered leg brace called the Nomad in 36 people who have trouble walking due to conditions like stroke, multiple sclerosis, or spinal cord injury. Participants will use the brace at home for three months to see if it improves their walking speed, balance, and q…
Sponsor: Shirley Ryan AbilityLab • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
-
Shocking muscles to move: new exercise hope for nerve disease patients
Symptom relief Recruiting nowThis study tests whether whole-body electrical muscle stimulation (WB-EMS) can help adults with neuromuscular diseases like ALS, SMA, and muscular dystrophy exercise safely. Because these conditions weaken the nerves that control muscles, traditional exercise is often too hard. W…
Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
-
Swiss study tracks childhood cancer Survivors' health for decades
Knowledge-focused Recruiting nowThis study follows 3,000 childhood cancer survivors in Switzerland to learn about long-term health problems caused by cancer treatments. Participants undergo physical exams, lab tests, and questionnaires during regular follow-up visits. The goal is to better understand and manage…
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC