Postpoliomyelitis syndrome
MONDO:0017416Postpoliomyelitis syndrome (PPS) is a neurologic disorder characterized by the development of new neuromuscular symptoms such as progressive muscular weakness or abnormal muscle fatigability occurring in survivors of the acute paralytic form of poliomyelitis, 15-40 years after recovery from the disease, and that is unexplained by other medical causes. Other manifestations that can occur gradually include generalized fatigue, muscle atrophy, muscle and joint pain, intolerance to cold, and difficulties sleeping, swallowing or breathing.
Also known as: Post Polio Syndrome, postpolio sequelae, postpolio syndrome, postpoliomyelitic syndrome, postpoliomyelitis sequelae, postpoliomyelitis syndrome, polio late effects, post polio syndrome
26 clinical trials for this condition and its sub-types, 11 tagged with Postpoliomyelitis syndrome itself.
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Lifting weights to fight transplant After-Effects: a new hope for young survivors
Disease control CompletedThis study looked at whether a 16-week strength training program can prevent or reduce late effects like muscle loss, heart disease, and diabetes in adults who had a bone marrow transplant as children. 28 survivors and a matched control group participated. The goal was to see if …
Sponsor: Rigshospitalet, Denmark • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Magnetic pulses may ease Post-Polio symptoms
Symptom relief CompletedThis study tested whether adding transcranial magnetic stimulation (TMS) to standard exercise can reduce fatigue, pain, and improve walking in people with postpolio syndrome. 26 adults who had polio earlier in life and now have new symptoms took part. Half got TMS plus exercise, …
Sponsor: Ege University • Aim: Symptom relief
Last updated Sep 12, 2026 00:00 UTC
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Web-Based insomnia treatment shows promise for childhood cancer survivors
Symptom relief CompletedThis study tested an online insomnia treatment program for adult survivors of childhood cancer. Over 1,500 survivors participated, using a web-based program that teaches healthy sleep habits and cognitive behavioral techniques. The goal was to see if improving sleep could also bo…
Sponsor: St. Jude Children's Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC