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Polymicrogyria

MONDO:0000087

A developmental brain abnormality characterized by an excessive amount of small convolutions on the surface of the brain and cognitive dysfunction.

1 clinical trial for this condition and its sub-types, 1 tagged with Polymicrogyria itself.

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Where it sits in the disease tree

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Part of

↑ Congenital nervous system disorder (284)

Sub-types of Polymicrogyria

Bilateral polymicrogyria 0 trials
5 sub-types
- Bilateral frontal polymicrogyria 0 trials Sub-types →
- Bilateral frontoparietal polymicrogyria 0 trials
- Bilateral generalized polymicrogyria 0 trials
- Bilateral parasagittal parieto-occipital polymicrogyria 0 trials
- Bilateral perisylvian polymicrogyria 0 trials Sub-types →
Unilateral polymicrogyria 0 trials
2 sub-types
- Unilateral focal polymicrogyria 0 trials
- Unilateral hemispheric polymicrogyria 0 trials

Most studied deeper sub-types

Complex cortical dysplasia with other brain malformations 7 (0) Polymicrogyria, bilateral perisylvian, autosomal recessive (0) Polymicrogyria, bilateral perisylvian, X-linked (0) Polymicrogyria, perisylvian, with cerebellar hypoplasia and arthrogryposis (0)

Including sub-types (1) Tagged with Polymicrogyria (1)

Trials to join now! 1

Can genes explain brain malformations?

Knowledge-focused Recruiting now

This study aims to understand the genetic causes of brain development disorders, including Aicardi syndrome, polymicrogyria, and Dandy-Walker malformation. Researchers will analyze genetic data from 2000 participants with these conditions, all confirmed by MRI. The goal is to use…

Sponsor: University of California, San Francisco • Aim: Knowledge-focused

Last updated Aug 19, 2026 00:00 UTC