Pleomorphic adenoma
MONDO:0008401A neoplasm characterized by the presence of benign epithelial and myoepithelial cells and a mesenchymal component that may contain mucoid, myxoid, cartilaginous, or osseous areas. It may be completely or partially encapsulated. It occurs in the parotid gland, submandibular gland, minor salivary glands in the oral cavity, upper respiratory tract, and nasal cavity and paranasal sinuses. It usually presents as a slow growing painless mass. Infrequently, patients may present with pain and facial palsy. It may recur after excision or transform to a malignant neoplasm (carcinoma ex pleomorphic adenoma).
Also known as: adenomas, salivary gland pleomorphic, somatic, pleomorphic adenoma, pleomorphic adenoma (morphologic abnormality), tumor, mixed, benign, Psa, Sgpa, mixed tumor of the salivary gland, mixed tumour of the salivary gland
1469 clinical trials for this condition and its sub-types, 12 tagged with Pleomorphic adenoma itself.
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New pill could ease psoriatic arthritis pain in 12 weeks
Disease control Recruiting nowThis study tests an experimental oral drug called D-2570 in 222 adults with active psoriatic arthritis. Participants take the drug or a placebo daily for 12 weeks. The main goal is to see if D-2570 reduces joint tenderness and swelling by at least 20% compared to placebo.
Phase 2 • Sponsor: InventisBio Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Can MRI outsmart blood tests for prostate cancer?
Diagnosis Recruiting nowThis study enrolls 950 men with suspected but undiagnosed prostate cancer who are scheduled for a biopsy. Researchers will compare the accuracy of prostate MRI against a panel of blood and urine biomarkers (PCA3, PSA, TMPRSS2:ERG) in detecting clinically significant prostate canc…
Sponsor: University of Michigan • Aim: Diagnosis
Last updated Aug 19, 2026 00:00 UTC
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Fewer needles, same safety? new study tests smarter prostate cancer detection.
Diagnosis Recruiting nowThis study tests whether men with very high PSA and suspicious MRI can safely skip the painful 12-needle systematic biopsy and rely only on targeted samples. Over 1,200 men will get both biopsies, but each sample is analyzed separately to see how often the extra needles find dang…
Sponsor: Shanghai East Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 14:03 UTC