Plasmacytoma
MONDO:0005615Plasmacytoma is a localized mass of neoplastic monoclonal plasma cells that represents approximately 5% of all plasma cell neoplasms. There are two separate entities: primary plasmacytoma of the bone and extramedullary plasmacytoma of the soft tissues. Of the extramedullary plasmacytomas, 80% occur in the head and neck, usually in the upper respiratory tract. The median age at diagnosis is 50 years and the male to female ratio is 3:1. Long-term survival is possible following local radiotherapy, particularly for soft tissue presentations.
Also known as: plasmacytoma, solitary plasmacytoma, anaplastic plasmacytoma, anaplastic skeletal plasmacytoma (type), anaplastic solitary extramedullary plasmacytoma of the cecum (type), extramedullary anaplastic plasmacytoma (type), myeloma - solitary, myeloma, solitary
1937 clinical trials for this condition and its sub-types, 9 tagged with Plasmacytoma itself.
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Sub-types of Plasmacytoma
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Extramedullary plasmacytoma 7 trials
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Solitary osseous plasmacytoma 4 trials
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Primary plasmacytoma of the bone 2 trials
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Solitary plasmacytoma of chest wall 0 trials
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Experimental Dual-Target CAR-T therapy takes aim at Hard-to-Treat plasma cell cancers
Disease control Recruiting nowThis early-phase trial is testing a new type of gene therapy called CAR 70-BCMA dual-target CAR-T for people with relapsed or refractory plasma cell neoplasms, including multiple myeloma. The therapy involves taking a patient's own immune cells, re-engineering them to recognize a…
Early phase 1 • Sponsor: The General Hospital of Western Theater Command • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Massive myeloma data bank launches to fuel future discoveries
Knowledge-focused Recruiting nowThis study is creating a large collection of blood samples, tissue, and health information from 2,500 people with plasma cell disorders like multiple myeloma. Researchers will use this repository to better understand how the disease develops and changes over time. No new treatmen…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC