Plasmablastic lymphoma

MONDO:0017347

An aggressive diffuse large B-cell lymphoma frequently arising in the setting of HIV infection and characterized by the presence of large neoplastic cells resembling B-immunoblasts which have the immunophenotypic profile of plasma cells. Sites of involvement include the oral cavity, sinonasal cavity, skin, soft tissues, gastrointestinal tract, and bone.

Also known as: PBL, Plasmablastic lymphoma, PLBL

2024 clinical trials for this condition and its sub-types, 20 tagged with Plasmablastic lymphoma itself.

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Where it sits in the disease tree

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Part of

↑ Diffuse large B-cell lymphoma (755) ↑ Epstein-Barr virus-associated lymphoproliferative disorder (713)

Including sub-types (2024) Tagged with Plasmablastic lymphoma (20)

Trials to join now! 8 Not yet recruiting 2 Not yet finished but already full! 6 Completed 3 Terminated 1

Experimental lymphoma drug shows early promise in tiny study

Disease control Stopped early

This study tested a drug called belantamab mafodotin (Blenrep) in 10 people with rare, aggressive lymphomas that had come back or not responded to treatment. The drug is an antibody-drug conjugate designed to target and kill lymphoma cells. The trial was terminated early, so the …

Phase 2 • Sponsor: Jacob Soumerai, MD • Aim: Disease control

Last updated Jun 27, 2026 11:01 UTC

Plasmablastic lymphoma

Where it sits in the disease tree

Experimental lymphoma drug shows early promise in tiny study