Plasma cell leukemia
MONDO:0018689An aggressive plasma cell neoplasm characterized by the presence of neoplastic plasma cells in the peripheral blood. It is characterized by the presence of a circulating clonal plasma cell count that exceeds 2x10^9/L or is 20% of the leukocyte differential count.
Also known as: PCL, leukaemia plasmacytic, leukemia plasmacytic, plasma cell leukemia, plasmacytic leukaemia, plasmacytic leukemia, leukemia, plasma cell
2045 clinical trials for this condition and its sub-types, 32 tagged with Plasma cell leukemia itself.
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New cocktail aims to tackle tough myeloma cases
Disease control CompletedThis study tested a combination of thalidomide, bortezomib, and high-dose melphalan followed by a stem cell transplant in 29 patients with advanced multiple myeloma who had already failed one round of treatment. The goal was to find the safest dose of thalidomide and see how well…
Phase 1/2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New hope for rare leukemia: aggressive combo therapy shows promise
Disease control CompletedThis phase 2 trial tested a powerful combination of chemotherapy drugs followed by stem cell transplants in 40 patients under 70 with primary plasma cell leukemia, a rare and aggressive blood cancer. The goal was to see if this intensive approach could improve how long patients l…
Phase 2 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 26, 2026 19:17 UTC
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Lab tests could pick the right drug for tough myeloma cases
Knowledge-focused CompletedThis study tests a new way to choose treatments for people with multiple myeloma or plasma cell leukemia that has returned or stopped responding to standard therapy. Researchers use a lab test that checks many drugs at once, along with genetic information, to find which drug or d…
Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC