Plantar fibromatosis
MONDO:0004684A superficial fibromatosis arising from soft tissue of the plantar regions. It is characterized by the presence of spindle-shaped fibroblasts, hypercellularity, and an infiltrative growth pattern.
Also known as: Ledderhose's disease, Lederhose disease, plantar fibromatosis, plantar part of pes superficial Fibromatosis, plantar part of pes superficial fibromatosis, superficial fibromatosis of plantar part of pes, plantar fascial fibromatosis
1428 clinical trials for this condition and its sub-types, 2 tagged with Plantar fibromatosis itself.
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New shot could ease pain of rare foot condition
Symptom relief CompletedThis phase 3 study tests an injection called EN3835 against a placebo for people with Ledderhose disease, which causes painful lumps on the soles of the feet. About 418 adults with foot pain from this condition will receive either the drug or a placebo. The main goal is to see if…
Phase 3 • Sponsor: Endo USA Inc., a Keenova Therapeutics Company • Aim: Symptom relief
Last updated Jul 15, 2026 00:00 UTC
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New shot could ease pain of plantar fibromatosis
Symptom relief CompletedThis study tested an injection called EN3835 against a placebo in 176 people with plantar fibromatosis, a condition causing painful lumps on the soles of the feet. The goal was to see if EN3835 reduces foot pain and improves daily function over 57 days. Participants received up t…
Phase 2 • Sponsor: Endo USA Inc., a Keenova Therapeutics Company • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC