Pituitary gland adenoma
MONDO:0006373A non-metastasizing tumor that arises from the adenohypophysial cells of the anterior lobe of the pituitary gland. The tumor can be hormonally functioning or not. The diagnosis can be based on imaging studies and/or radioimmunoassays. Due to its location in the sella turcica, expansion of the tumor mass can impinge on the optic chiasm or involve the temporal lobe, third ventricle and posterior fossa A frequently associated physical finding is bitemporal hemianopsia which may progress to further visual loss.
Also known as: adenoma of pituitary, adenoma of pituitary gland, adenoma of the pituitary, adenoma of the pituitary gland, adenoma, anterior lobe pituitary gland, benign, pituitary adenoma, pituitary gland adenoma, PTAD
1588 clinical trials for this condition and its sub-types, 34 tagged with Pituitary gland adenoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Pituitary gland adenoma
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Familial isolated pituitary adenoma 1 trial · 31 incl. sub-types
6 sub-types
- Cushing disease due to pituitary adenoma 23 trials
- Prolactin-producing pituitary gland adenoma 11 trials
- Growth hormone secreting pituitary adenoma 1 1 trial
- Pituitary adenoma 3, multiple types 0 trials
- Pituitary adenoma 5, multiple types 0 trials
- Pituitary adenoma, growth hormone-secreting, 2 0 trials
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Functioning pituitary gland adenoma 1 trial · 24 incl. sub-types
5 sub-types
- Cushing disease due to pituitary adenoma 23 trials
- TSH producing pituitary tumor 0 trials · 2 incl. sub-types Sub-types →
- Nelson syndrome 0 trials
- Functioning gonadotropic adenoma 0 trials
- Mixed functioning pituitary adenoma 0 trials Sub-types →
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Non-functioning pituitary adenoma 8 trials · 9 incl. sub-types
2 sub-types
- Silent pituitary adenoma 1 trial
- Null pituitary adenoma 0 trials
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1 sub-type
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Chromophobe adenoma 0 trials
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Pituitary gland acidophil adenoma 0 trials
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Pituitary gland basophil adenoma 0 trials
Most studied deeper sub-types
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Could a simple drug during brain surgery prevent Life-Threatening sodium swings?
Disease control By invitation onlyThis trial tests whether giving a low-dose infusion of desmopressin (dDAVP) during surgery for complex brain tumors around the pituitary gland can prevent dangerously high sodium levels (hypernatremia) in the first 24 hours after surgery. High sodium can cause brain bleeding, sei…
Phase 4 • Sponsor: Zhaoyun Zhang • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Super-Sharp brain scanner could revolutionize diagnosis of dementia and cancer
Diagnosis By invitation onlyThis study compares a new ultra-high resolution PET/CT scanner, the NeuroEXPLORER, with standard clinical PET/CT scanners for imaging the head and neck. Researchers aim to see if the new device provides more detailed images to improve diagnosis of conditions like dementia, Parkin…
Sponsor: prof. dr. Koen Van Laere • Aim: Diagnosis
Last updated Jun 27, 2026 12:36 UTC
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New scan could spot hidden tumors more accurately
Diagnosis OngoingThis study tests whether a new type of PET/CT scan, using a radioactive tracer called 68Ga-DOTATOC, can find neuroendocrine tumors (NETs) and similar tumors more safely and accurately than current imaging methods. About 800 people with known or suspected NETs will receive the sca…
Sponsor: British Columbia Cancer Agency • Aim: Diagnosis
Last updated Jun 27, 2026 12:31 UTC
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New scan could spot pituitary tumors more clearly
Diagnosis By invitation onlyThis early-phase study tests a new radioactive tracer called [68Ga]Ga-NOTA-RF for PET scans in 30 people with pituitary tumors. The goal is to see if this tracer can better highlight tumors and help doctors tell different tumor types apart. Participants receive an injection of th…
Early phase 1 • Sponsor: Peking Union Medical College Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 08:00 UTC
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Brain radiation and memory: new study maps hidden risks
Knowledge-focused OngoingThis study follows 75 adults with benign or slow-growing brain tumors who are receiving partial brain radiation. Researchers will use memory tests and MRI scans before treatment and at 6 and 12 months after to see how radiation affects thinking and memory. The goal is to identify…
Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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New PET tracer could light up brain tumors
Knowledge-focused OngoingThis phase 1 study tests a new PET imaging tracer called 89Zr-cRGDY in 17 people with malignant brain tumors or pituitary adenomas. The tracer is given in a very small dose to see how it spreads and clears from the body. The goal is to improve brain tumor imaging, not to treat th…
Phase 1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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New model aims to predict Post-Surgery headaches in pituitary patients
Knowledge-focused OngoingThis study looks at 500 adults having pituitary tumor surgery through the nose. Researchers want to find out who gets headaches soon after surgery and build a tool to predict that risk. Participants report their pain daily and fill out surveys for up to 3 months after surgery.
Sponsor: Beijing Tiantan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC