Pilocytic astrocytoma
MONDO:0016691Pilocytic astrocytoma is a rare subtype of low-grade glioma of the central nervous system characterized by a well circumscribed, often cystic, brain tumor with a discrete mural nodule and long, hair-like projections that extend from the neoplastic astrocytes. Depending on the primary localization and the size of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), blurred vision, decreased visual acuity, ataxia and/or nystagmus, among others. It is most commonly located in the cerebellum, but occurrence in the hypothalamus, brain stem, optic chiasma, and hemispheres has also been reported.
Also known as: astrocytoma, benign, astrocytoma, pilocytic, benign, grade I astrocytic neoplasm, grade I astrocytic tumor, grade I astrocytic tumour, grade I astrocytoma, pilocytic astrocytoma
1465 clinical trials for this condition and its sub-types, 12 tagged with Pilocytic astrocytoma itself.
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Sub-types of Pilocytic astrocytoma
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Pilomyxoid astrocytoma 5 trials
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Childhood pilocytic astrocytoma 1 trial
1 sub-type
- Juvenile pilocytic astrocytoma 0 trials
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Cerebellar pilocytic astrocytoma 0 trials
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Drug everolimus shows promise in slowing Children's brain tumors
Disease control CompletedThis study tested the drug everolimus in 65 children whose low-grade gliomas had come back or worsened. The goal was to see if the drug could stop or slow tumor growth. Children took everolimus pills daily, and doctors tracked tumor changes with MRI scans. The study focused on ho…
Phase 2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 26, 2026 14:47 UTC
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New brain scan could sharpen surgery for glioma patients
Knowledge-focused CompletedThis pilot study tested whether a special PET scan using 18F-FDOPA can help doctors better plan surgery and radiation for people with newly diagnosed brain tumors (gliomas). Twenty-four adults took part at Mayo Clinic. The goal was to see if the scan provides useful information b…
Early phase 1 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:06 UTC