Photosensitivity disease
MONDO:0006597Abnormal responses to sunlight or artificial light due to extreme reactivity of light-absorbing molecules in tissues. It refers almost exclusively to skin photosensitivity, including sunburn, reactions due to repeated prolonged exposure in the absence of photosensitizing factors, and reactions requiring photosensitizing factors such as photosensitizing agents and certain diseases. With restricted reference to skin tissue, it does not include photosensitivity of the eye to light, as in photophobia or photosensitive epilepsy.
Also known as: disorder, photosensitivity, disorders, photosensitivity, photodermatitides, photodermatitis, photodermatosis, photosensitivity disorder, photosensitization
7 clinical trials for this condition and its sub-types, 4 tagged with Photosensitivity disease itself.
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Sub-types of Photosensitivity disease
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Polymorphic light eruption 1 trial
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Photoallergic dermatitis 0 trials
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Phototoxic dermatitis 0 trials
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Skin sensitivity to sun 0 trials
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Heartburn drug could ease painful sun sensitivity
Disease control CompletedThis Phase 2 trial tested whether oral cimetidine (Tagamet), a common heartburn drug, can reduce light sensitivity in people with erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLP). These genetic conditions cause severe pain from sunlight exposure. The study en…
Phase 2 • Sponsor: Amy K. Dickey, M.D. • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Cheap drugs may tame severe sun allergy
Disease control CompletedThis completed study tested two older, low-cost drugs—methotrexate and azathioprine—against chronic actinic dermatitis, a painful skin reaction to sunlight. Fifty adults were randomly assigned to one drug for 24 weeks. Researchers tracked eczema severity and safety. The goal was …
Early phase 1 • Sponsor: Pak Emirates Military Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC