Peyronie disease

MONDO:0008231

A condition characterized by hardening of the penis due to the formation of fibrous plaques on the dorsolateral aspect of the penis, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both.

Also known as: Peyronie disease, Peyronie's disease, Peyronie's fibromatosis, penile fibromatosis, penile induration, penis fibromatosis

1444 clinical trials for this condition and its sub-types, 12 tagged with Peyronie disease itself.

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Where it sits in the disease tree

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Part of

↑ Hereditary disorder of connective tissue (1314) ↑ Penile neoplasm (65) ↑ Superficial Fibromatosis (34)

Including sub-types (1444) Tagged with Peyronie disease (12)

Trials to join now! 4 Not yet recruiting 1 Not yet finished but already full! 4 Completed 3

Scientists grow penile tissue in lab for first human trial

Disease control Not yet recruiting

This early-stage trial tests a lab-grown penile tissue made from a man's own cells to repair severe, irreversible damage to the penis. Ten men aged 18-60 who have failed standard treatments will receive the implant. The main goal is to check safety, not effectiveness.

Phase 1 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control

Last updated Jun 27, 2026 12:01 UTC

Peyronie disease

Where it sits in the disease tree

Scientists grow penile tissue in lab for first human trial