Persistent truncus arteriosus
MONDO:0018072A rare congenital cardiovascular disorder characterized by the failure of the embryologic structure truncus arteriosus to divide into the aorta and pulmonary trunk. It results in the presence of a single vessel instead of two vessels leading out of the heart. Clinical signs and symptoms include cyanosis that is present at birth, poor growth, dyspnea, tachypnea, arrhythmia, cardiomegaly, and heart failure. If it is not surgically repaired, it leads to death.
Also known as: TAC, Truncus Arteriosus, common aorticopulmonary trunk, common arterial trunk, common truncus arteriosus, persistent truncus arteriosus, persistent truncus arteriosus (disease), truncus arteriosus
82 clinical trials for this condition and its sub-types, 8 tagged with Persistent truncus arteriosus itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Persistent truncus arteriosus
-
New balloon treatment for leg artery disease shows promise in Real-World study
Disease control By invitation onlyThis study follows 300 people with blocked leg arteries who received a treatment using a balloon coated with paclitaxel and vitamin E. The goal is to see if the balloon keeps the artery open and prevents the need for repeat procedures over one year. Participants are adults with m…
Sponsor: Genoss Co., Ltd. • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
-
New balloon treatment for blocked leg arteries tested in Real-World study
Disease control By invitation onlyThis study is tracking 200 people with blocked leg arteries who are receiving a special balloon coated with the drug paclitaxel (GENOSS PCB). The balloon is inflated inside the artery to open it and release the drug, which helps prevent the artery from narrowing again. Researcher…
Sponsor: Genoss Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
-
New app aims to ease Parents' stress over Baby's heart surgery decision
Symptom relief OngoingThis study tests whether a web-based decision aid app can reduce stress and improve decision-making for parents whose baby is diagnosed with a life-threatening congenital heart defect. 135 parents are randomly assigned to use the app alone or with an added values clarification ex…
Sponsor: University of Utah • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC