Peptic esophagitis

This phase 3 trial tests whether tegoprazan, a stomach acid blocker, can prevent gastrointestinal complications like bleeding and ulcers in people who have had an ischemic stroke and are taking antiplatelet drugs (blood thinners). About 1,500 adults in South Korea will receive ei…

This study tests whether a newer acid-reducing drug, Vonaprazan, heals acid reflux better than the standard drug Esomeprazole in people who had POEM surgery for achalasia. About 300 adults with moderate to severe esophagitis will take one of the two drugs for 8 weeks. The goal is…

This study compares two doses of vonaprazan (10 mg and 20 mg) with esomeprazole 40 mg for healing moderate to severe reflux esophagitis (grades B, C, or D) over 8 weeks. About 414 adults with GERD symptoms for at least 4 weeks will be randomly assigned to one of the three groups.…

This study tests a new medicine called anaprazole to see if it heals the esophagus better than a standard treatment (rabeprazole) in people with reflux esophagitis. About 500 adults with moderate to severe esophagus damage will take either anaprazole or rabeprazole daily for up t…

Researchers are running an observational registry to study whether vonoprazan, an oral drug for heartburn and acid reflux, is safe to take during pregnancy. The study follows women aged 15 to 50 who took vonoprazan while pregnant and compares their outcomes with women who did not…

This study looks at the stomach and esophagus of people living at high altitude in Zaduo County, comparing them with similar patients from lower-altitude Jilin Province. The goal is to see if high-altitude residents have different patterns of conditions like reflux esophagitis an…