Pediatric acute-onset neuropsychiatric syndrome
MONDO:1060178An autoimmune disorder that involves a constellation of psychiatric and neurologic symptoms that present simultaneously and in rapid onset, the cause or causes of which are unknown. Although the cause is still under investigation, the manifestations may follow a recent infection.
Also known as: PANS
48 clinical trials for this condition and its sub-types, 8 tagged with Pediatric acute-onset neuropsychiatric syndrome itself.
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Browse by category →Sub-types of Pediatric acute-onset neuropsychiatric syndrome
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PANDAS 6 trials
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Could a monthly IVIG infusion ease severe OCD in kids with PANS?
Disease control CompletedThis study tested a monthly dose of intravenous immunoglobulin (IVIG) for 6 months in 17 children aged 4–17 with Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), a condition marked by sudden, severe OCD or food refusal. Researchers measured changes in symptom severity and …
Phase 2 • Sponsor: Göteborg University • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Can a Low-THC cannabis extract calm the sudden psychiatric storm of PANS?
Symptom relief CompletedResearchers are testing a full-spectrum medicinal cannabis extract called NTI164, which contains 0.08% THC, in children with pediatric acute-onset neuropsychiatric syndrome (PANS). PANS causes sudden, severe obsessive-compulsive symptoms, restricted eating, and other psychiatric …
Phase 1/2 • Sponsor: Fenix Innovation Group • Aim: Symptom relief
Last updated Sep 11, 2026 00:00 UTC
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Could an immune treatment ease severe OCD in kids with PANS?
Symptom relief CompletedThis study tested whether a medicine called Panzyga (given through a vein) can reduce obsessive-compulsive symptoms in children aged 6 to 17 with a condition called PANS or PANDAS. These children experience a sudden, severe onset of OCD and other neuropsychiatric problems. The st…
Phase 3 • Sponsor: Octapharma • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Hidden costs of PANS: new study reveals financial toll of IVIG treatment
Knowledge-focused CompletedThis completed study surveyed 65 U.S. families to understand the economic and quality-of-life impact of IVIG treatment for PANS/PANDAS. Researchers asked about medical visits, insurance, work absences, and children's school attendance. The goal is to shed light on the hidden cost…
Sponsor: Brain Inflammation Collaborative • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:31 UTC